Studies
Dual PD-1/VEGF Bispecific Antibody Extends Survival Over Standard Immunotherapy in Lung Cancer
For the roughly 30% of non-small-cell lung cancer cases classified as squamous histology — a subtype historically less…
Longevity
Aging Microglia Dysfunction Linked to Chronic Pain via Kinin Receptor Pathway
Chronic pain in older adults is vastly underdiagnosed and undertreated, partly because its biological roots in aging…
Studies
PDE4D Enzyme Drives B Cell Invasion in Sjögren's Syndrome Glands
For the estimated four million Americans living with primary Sjögren's syndrome — a chronic autoimmune disease that…
Studies
Colorectal Tumors May Inadvertently Protect Arteries Via Arginine-T-Cell Axis
A counterintuitive intersection between oncology and cardiovascular biology is emerging: the metabolic environment…
Wellbeing
Youth Concussion Recognition in Sports: Role of Parents, Coaches, and Education Highlighted in Review
Sport-related concussion in young athletes is widely recognized as a risk, yet the scale of underreporting remains one…
Studies
p16-High Immune Cells Link COVID Vaccine to Broad Disease Tolerance
The longstanding assumption that surviving an infection depends almost entirely on killing pathogens faster than they…
Studies
Ugandan Malaria Parasite Evolves PX1 Haplotype Reducing Antimalarial Susceptibility
Antimalarial drug resistance has toppled treatment regimens before — chloroquine's collapse reshaped global malaria…
Studies
Artemisinin Resistance Mutations Reach 5% Prevalence Across East Africa
The quiet erosion of artemisinin's effectiveness — the backbone of malaria treatment worldwide — is now measurable at…
Studies
Two-Dose mRNA RSV Vaccine Shows Durable Immunogenicity in Transplant Recipients
For the estimated 500,000+ solid organ transplant recipients living in the United States, respiratory syncytial virus…
Fitness
Molecular Autopsy Reveals Hidden Arrhythmia Genes Behind Athlete Sudden Death
When a young athlete collapses and dies on a field, the tragedy extends far beyond one individual — because the…
Studies
GLP-1 Drugs Show Benefits Across 14 Conditions Beyond Weight Loss
The prevailing assumption that obesity drugs work simply by shrinking waistlines is increasingly difficult to defend…
Studies
AI Pipeline Identifies GPNMB as Cross-Cancer CAR T-Cell Target
The central challenge of CAR T-cell therapy has never been engineering the immune weapon itself — it has been knowing…
Studies
Foodborne Parasites Still Cause Nearly 5 Million Lost Life-Years Annually
Parasitic infections transmitted through food remain a vastly underappreciated contributor to global disease burden…
Wellbeing
Psychotherapy Shows Large PTSD Effect in Adolescent Sexual Abuse Survivors
Trauma-focused psychotherapy for adolescents who have experienced penetrative sexual abuse remains severely…
Wellbeing
Emotion Regulation Deficits Strongly Associated with Insomnia Severity in Adults With ADHD
Sleep problems in ADHD are often attributed to hyperarousal or circadian misalignment, but a growing body of evidence…
Studies
Salivary HHV-6 Viral Load Correlates With Long COVID Symptom Severity Scores
The persistent, often debilitating symptom burden of Long COVID remains mechanistically poorly understood, yet…
Studies
DECISION Trial: Low-Dose Digoxin Misses Primary Endpoint in 1,001-Patient Heart Failure RCT
Heart failure management has changed dramatically over the past three decades, yet digoxin — one of medicine's oldest…
PREPRINTLongevity
Irregular Sleep Linked to Higher Mortality Risk in Men: UK Biobank Study Suggests Sex Differences
Analyzing 506,582 person-days of accelerometer recordings from 73,647 UK Biobank participants followed for over…
PREPRINTStudies
235,571-Person BRFSS Analysis Quantifies Diabetes, Smoking, and Income as Top Stroke Predictors
A pooled cross-sectional analysis of 235,571 U.S. adults from the 2021–2023 Behavioral Risk Factor Surveillance System…
PREPRINTWellbeing
Untreated Hearing Loss Linked to Higher Depressive Symptoms and Reduced Friend Contact in Older Adults
Among 2,049 Black and White adults aged 70–79 in the Health, Aging, and Body Composition Study, objective hearing loss…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.