PREPRINTLongevity
355K-Person UK Biobank Multi-Omic Study Maps CKM Syndrome Stages to CVD via Statistical Mediators
Across 355,724 UK Biobank participants followed for a median 13.5 years, a multi-omic analysis mapped…
PREPRINTLongevity
10 Plasma Immune Markers Inversely Linked to Alzheimer's Tau/Amyloid Ratio, With Sex Differences Emerging
In a cross-sectional cohort of 261 participants from the Cleveland Clinic Lou Ruvo Center Biobank, ten plasma…
Longevity
GLP-1 Incretin Therapy Associated With 54% Lower Alzheimer's Incidence in 57,800-Patient EHR Study
In a propensity-score matched cohort of 57,802 adults aged 50+ with documented Alzheimer's risk factors drawn from 29…
Longevity
Mediterranean Lifestyle Associated with 51% Lower CVD Death Risk in Type 2 Diabetics
Among 3,612 UK Biobank participants with type 2 diabetes followed for up to 12.1 years, those in the highest quartile…
Studies
Beyond BMI: Endocrine Society Weighs New Obesity Classification Framework's Clinical Trade-offs
How obesity is defined shapes who gets treated, when, and with what urgency — making the Lancet Diabetes &…
Fitness
Self-Balancing Exoskeleton Shows Safety and Usability Gains in Complete Paraplegia
For the roughly 300,000 Americans living with spinal cord injury, the gap between laboratory promise and real-world…
Longevity
UC-MSC Secretome Suppresses MMP-13 and ADAMTS-5 in Osteoarthritis Models
The secretome of umbilical cord-derived mesenchymal stem cells (UC-MSCs) — encompassing soluble paracrine factors and…
Studies
mPFC Neural Ensembles Show Stable Temporal Sequences During Decision-Making
Understanding how the brain converts incoming sensory signals into a deliberate choice has long been a central puzzle…
Studies
Ebola in Pregnancy: Maternal Survival Improves, But Neonatal Risk Remains Severe
For clinicians and public health professionals tracking emerging infectious threats, the intersection of Ebola virus…
Studies
Tirzepatide's Dual GIP/GLP-1 Action Shows Promise for MASH Fibrosis in Phase 2 Trial
Tirzepatide, a first-in-class dual GIP/GLP-1 receptor agonist, is generating clinical signals that extend well past…
Studies
Nirsevimab Cuts Infant RSV ICU Admissions by 57% in Belgian National Data
Respiratory syncytial virus has long been the leading infectious cause of infant hospitalization in high-income…
Longevity
Myasthenia Gravis Patients Outlive General Population by Nearly Five Years
Two neuromuscular diseases with overlapping immune-mediated mechanisms can have strikingly opposite effects on…
Fitness
Peptide Doping Review Exposes Cardiovascular and Metabolic Risks Beyond Elite Sport
The assumption that newer means safer is a persistent blind spot in performance enhancement culture. As peptide…
Longevity
Youth Plasma Protein TIMP2 Reverses Age-Driven Microglial Dysfunction in Mice
The immune cells of the aging brain may hold a key to understanding why age is the dominant risk factor for…
Longevity
Blood Protein TIMP2 Reverses Age-Driven Microglial Inflammation in Mouse Brains
The gap between understanding why aging is the dominant risk factor for neurodegenerative disease and actually…
Studies
Meta-Analysis Links Elevated BMI to 19 Cancer Types, Including Four Newly Identified
Understanding which cancers are genuinely driven by excess body fat — and which associations are artifacts of…
Studies
Germline Testing and Polygenic Risk Together Reshape Cancer Prevention Strategies
The gap between what genetic science now knows about cancer risk and what most clinicians actually apply in practice…
Studies
Socioeconomic Deprivation Doubles Mortality Risk in Children With Congenital Anomalies
The survival gap between wealthy and impoverished families is not just a feature of adult chronic disease — it shapes…
Studies
Platelet Protein RIP2 Acts as Internal Brake on Dangerous Clot Formation
The molecular machinery governing how platelets decide when to form a clot—and when to stop—sits at the center of…
Studies
How Maternal RSV Antibodies Cross the Placenta to Shield Newborns
Respiratory syncytial virus hospitalizes hundreds of thousands of infants annually, yet newborns lack the immune…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.