Studies
Cholesterol Receptor LDLR Serves as Hepatitis A Viral Entry Point
Understanding viral entry mechanisms matters beyond infectious disease—it reveals how pathogens exploit fundamental cel…
Longevity
Mouse Brain Networks Mirror Human Aging Patterns in Landmark Cross-Species Study
Understanding how brain networks deteriorate with age has been hampered by the fundamental challenge of studying living…
Studies
CBLB Protein Blocker Disrupts Cancer Cell Movement Through EGFR Pathway
Cancer cells rely on sophisticated molecular machinery to migrate through tissues and establish metastases. This cellul…
Studies
CALHM5 Ion Channel Deletion Prevents Aortic Aneurysms Through Calcium Control
Aortic aneurysms represent one of cardiovascular medicine's most dangerous silent threats, often remaining undetected u…
Studies
Baboon Protein Engineering Shields Mice From Deadly Trypanosome Parasites
The evolutionary arms race between humans and deadly African sleeping sickness parasites may have just revealed a power…
Studies
Muscle Loss Predicts Worse Outcomes in Acute Pancreatitis Patients
The connection between muscle health and recovery from serious illness extends beyond the ICU to conditions like acute…
Supplements
Omega-3 Shows Limited Reversal of Propionic Acid Brain-Gut Damage
Omega-3 fatty acid supplementation reduced interleukin-6 levels by an unspecified amount in aged rats exposed to propio…
Longevity
Review Links Senescent Fat Cells to Breast Cancer Promotion Via SASP in 'Reverse Cardio-Oncology' Paradigm
European researchers have mapped how senescent (aged) fat cells actively promote breast cancer through a senescence-ass…
Longevity
Dasatinib-Quercetin Combo Reduces Age-Related Alveolar Bone Loss in Mice
Monthly treatment with dasatinib (5 mg/kg) and quercetin (50 mg/kg) prevented alveolar bone loss in aged mice over 10 m…
Wellbeing
South Asian Home Care Clients Show Half the Odds of Depression Diagnosis Despite Similar Symptoms
Mental health disparities in aging populations reveal troubling gaps that could leave thousands of older adults without…
Studies
Cord Blood Transplants Offer Viable Alternative for Rare Immune Disorder CGD Despite Graft Failure Risks
Children born with defective infection-fighting cells now have a viable treatment path when traditional bone marrow don…
Wellbeing
Nearly Half of Nurses Experience Disruptive Shift Work Sleep Disorder
Healthcare systems worldwide may be underestimating a critical workforce health crisis that directly impacts patient ca…
Studies
Nicotine Pouches Deliver Similar Levels to FDA-Approved Cessation Therapies
The explosive growth of tobacco-free nicotine pouches represents a potential paradigm shift in harm reduction, offering…
PREPRINTStudies
HbE Thalassemia Variant Linked to 38% Higher Prediabetes Diagnosis Risk Due to Elevated HbA1c in 43,088 British South Asians
Analysis of 43,088 British Bangladeshi and Pakistani participants revealed that rs33950507, a variant causing HbE thala…
PREPRINTWellbeing
PCOS Pain Affects 20.67% of Women with PCOS, Associated with Higher Risks of Infertility, Diabetes and More
Analysis of over 103 million women's health records reveals that 20.67% of those with polycystic ovary syndrome (PCOS)…
PREPRINTFitness
Exercise Benefits Peak at 45: Intensity vs Volume Varies by Sex
Wrist-worn accelerometer data from 8,661 adults tracked over nearly 7 years reveals striking age and sex differences in…
PREPRINTFitness
Physical Activity Linked to Greatest Mortality Risk Reduction Among Treated Hypertension Patients
Cross-national analysis of 70,849 participants found that moderate-to-vigorous physical activity delivered the stronges…
PREPRINTStudies
Single-Dose Oral Cholera Vaccine Shows 98% Effectiveness in Malawi Outbreak
A single dose of oral cholera vaccine achieved 98% effectiveness in preventing cholera infections during Malawi's devas…
PREPRINTWellbeing
Human-Induced Climate Change Accounts for 51-94% of Greece Heatwave Deaths
Analysis of over 2.1 million deaths across Greece from 2000-2019 reveals heatwaves increase mortality risk by 8-15%, wi…
PREPRINTNutrition
Pescatarian Diet Causally Reduces Fasting Insulin by 0.10 pmolL-1
Mendelian randomization analysis using genome-wide genetic variants as instrumental variables demonstrates that pescata…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.