PREPRINTWellbeing
Religiosity Cuts Fibrinogen But Raises HbA1c in 6,844 Adults Over Time
Among 6,844 English adults aged 50+ tracked across four waves of the English Longitudinal Study of Ageing, greater…
Studies
Meta-Analysis Identifies Distraction Methods That Cut Vaccine Distress Across Ages
Needle anxiety is one of the most common barriers to vaccination compliance across the lifespan, yet clinical…
Studies
PFA Beats Antiarrhythmic Drugs as First-Line AFib Treatment in RCT
For the millions of adults living with persistent atrial fibrillation, the standard first-line approach—trying…
Studies
Copper IUD Tops Emergency Contraception Rankings in 92-Trial Network Analysis
For the millions of women worldwide who face unintended pregnancy risk after unprotected intercourse, the relative…
Studies
Radiotheranostics Merges Imaging and Radiation to Personalize Cancer Treatment
Precision oncology is undergoing a structural shift — not from a single drug breakthrough, but from an entire…
Studies
Trisomy 21 Drives Chronic Interferon Overactivation, Undermining Vaccine-Induced Immunity
For the roughly 6 million people worldwide living with Down syndrome, the immune system has long been understood as…
Studies
Treg and MSC Cell Therapies Show Promise but Inconsistent Results for Chronic GVHD
For the estimated 30–50% of allogeneic stem cell transplant recipients who develop chronic graft-versus-host disease…
Longevity
Flattened Daily Cortisol Curve Linked to Alzheimer Risk in Diverse Cohort
The daily rhythm of stress hormones may quietly shape how the aging brain deteriorates — and new evidence from one of…
Nutrition
Quinoa's Kaempferol Inhibits mTOR, Cuts Amyloid-β in Rat Brain Aging Model
In a five-group rat model of accelerated brain senescence — combining D-galactose administration with fractionated…
Longevity
Plant Polysaccharide Extends Lifespan via DAF-16/FOXO and SKN-1/Nrf2 in Two Species
Polysaccharides extracted from Pausinystalia macroceras (PMP) extended lifespan and preserved healthspan in both C…
Studies
U.S. Child Health Trends Declining Across Multiple Developmental Domains
A generation of American children may be growing up fundamentally less healthy than their predecessors — not from a…
Longevity
Octogenarian 'Super Movers' Show 50% Lower Cognitive Decline Risk Via Preserved Brain Structure
Walking speed in your eighties turns out to be far more than a measure of physical fitness — it may serve as a window…
Studies
Half of MCI and Dementia Patients May Use Potentially Harmful Medications Pre-Diagnosis
For the millions of adults living with early cognitive decline, the medications prescribed for other health conditions…
Studies
Bundibugyo Ebola Variant Cleared in 22 Days With Dual Antibody-Antiviral Regimen
For a family of hemorrhagic fever viruses with fatality rates that can exceed 50%, even a single well-documented…
Studies
Bundibugyo Ebolavirus Lacks Licensed Countermeasures Despite Recurring Outbreak Threat
When a known pathogen resurfaces with no approved vaccine or treatment, the medical preparedness gap becomes…
PREPRINTLongevity
1,871-Person Lebanese Cohort Links Late-Life Learning to Dementia Risk Factors
A newly established Lebanese cohort of 1,871 adults aged 50+ (mean age 65.6, 70.1% women) is now tracking whether…
PREPRINTStudies
9-Metal Prenatal Mix Alters Teen Brain Risk Circuits via Timing-Specific Windows
Using a novel tooth-biomarker method, weekly metal concentrations in deciduous dentine — spanning 19 weeks pre-birth…
PREPRINTLongevity
27-Locus WMH Polygenic Score Links Sphingolipids, Cilia to Stroke Risk
A large-scale genomic analysis of white matter hyperintensities (WMH) — the brain's most common MRI marker of small…
PREPRINTLongevity
SuperAgers in 3,513-Person Cohort: Hypertension Control, Diet & Social Ties Predict Exceptional Cognition
Among 3,513 adults in the UK Whitehall II cohort, individuals who maintained youthful cognitive performance into late…
PREPRINTFitness
60% Lower Cardiometabolic Multimorbidity Risk Linked to Higher Fitness Across 3 Nations
Across 12,944 older adults in three nationally representative cohorts — China's CHARLS, England's ELSA, and the US HRS…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.