Fisetin Senolytic Treatment Reverses Age-Related Endothelial Dysfunction Partially Via CXCL12 in Old Mice
Fisetin supplementation at 100 mg/kg daily reversed age-related blood vessel dysfunction in 27-month-old mice by target…
Fisetin supplementation at 100 mg/kg daily reversed age-related blood vessel dysfunction in 27-month-old mice by target…
Researchers identified 5-androstene-3β,17β-diol (ADIOL), a steroid hormone discovered nearly 100 years ago, as the mole…
Mental health research has long struggled with a fundamental puzzle: how do thousands of genetic variants scattered acr…
Heart failure patients may soon have access to more precise prognostic tools through a simple blood test that measures…
A dramatic shift in global health patterns emerges from three decades of mortality tracking, with respiratory infection…
The brain's ability to maintain proper protein function may deteriorate earlier in aging than previously recognized, bu…
Cardiovascular disease remains the world's leading killer despite decades of advances in cholesterol management, largel…
Genetic predisposition to kidney disease just became more actionable. Adults carrying high-risk APOL1 gene variants—pre…
The trajectory toward global population stabilization carries profound implications for aging societies and healthcare…
Permanent genetic modifications to lower cholesterol could revolutionize cardiovascular prevention, potentially elimina…
Kidney stone prevention has long relied on the simple advice to 'drink more water,' yet most patients struggle to maint…
Most kidney stone sufferers understand they should drink more water, yet half experience recurrent stones within five y…
A critical immune signaling protein may explain why obesity triggers such widespread metabolic damage across multiple o…
Researchers developed Amylo-Detect, a machine learning model that analyzes electronic health records to identify patien…
Among 10,666 Medicare beneficiaries with chronic limb-threatening ischemia undergoing major lower-extremity amputation,…
The CMR GUIDE trial protocol outlines a precision approach to preventing sudden cardiac death by using cardiac magnetic…
Analysis of 6,323 adults without baseline coronary artery disease found that poor R-wave progression (PRWP) on electroc…
Researchers successfully replaced 16-26 liters of blood plasma from 12 mild cognitive impairment patients with plasma f…
This comprehensive review identifies how myofibroblasts expressing periostin, tenascin C, thrombospondin, and osteopont…
DNA methylation patterns in blood samples from 216 HIV patients with well-controlled infections revealed that specific…
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