Longevity
Cardiorespiratory Fitness Outperforms Self-Reported Activity in Predicting Longevity
Most adults track their health by counting steps or logging gym sessions — but the biological measure of how…
Studies
CAC Zero Score Does Not Eliminate Risk When Lipoprotein(a) Is Elevated
For years, a coronary artery calcium score of zero has been used as a powerful reassurance tool — effectively a…
Studies
Oral GLP-1 Pill Achieves 11% Weight Loss Without Injectable Delivery
The dominant barrier to GLP-1 receptor agonist therapy has never been efficacy — it has been the needle. Injectable…
Longevity
QSP Model Identifies Two Distinct Drug Combos: Metabolic vs. Longevity Optimization
A quantitative systems pharmacology model integrating four mechanistic layers — metabolic/pharmacodynamic responses…
Longevity
Metainflammation Bridges Preclinical Obesity to CVD via 3 Interdependent Mechanisms
A conceptual framework from Heilongjiang University positions metainflammation — chronic low-grade inflammation…
Studies
Low AlloMap Scores Linked to Higher Post-Transplant Cancer Risk
For heart transplant patients, the long shadow of immunosuppression doesn't end with rejection prevention — it extends…
Studies
Higher Clomiphene Doses Linked to Dose-Dependent Miscarriage and Stillbirth Risk in IVF
For the millions of women undergoing fertility treatment, the assumption that more medication means better outcomes is…
Studies
Lecanemab in Chinese Real-World Use: ARIA Rates and Biomarker Shifts at Six Months
As anti-amyloid therapy moves from clinical trials into everyday medical practice, the gap between controlled trial…
Studies
Emerging Evidence Links Mitophagy Dysfunction to Liver Fibrosis Progression
Liver fibrosis affects hundreds of millions of people globally and currently lacks approved pharmacological treatments…
Studies
FL118 Molecular Glue Degrades Two Cancer Proteins Simultaneously in Hard-to-Treat Tumors
For cancers that resist nearly every available treatment — glioblastoma, pancreatic ductal adenocarcinoma, metastatic…
Studies
Protein Interaction Networks Emerge as Precision Targets in Ischemic Stroke Therapy
Ischemic stroke remains one of the leading causes of death and long-term disability worldwide, yet the therapeutic…
Studies
CD19 CAR T Cells Survive Over a Decade Post-Infusion in Lymphoma Patients
One of the most persistent questions in cancer immunotherapy has been whether engineered T cells can sustain long-term…
Nutrition
14-Year Guangxi Data Links Folic Acid Compliance to 97% NTD Correlation Drop
Neural tube defects remain one of the most preventable categories of congenital disability worldwide, yet gaps in…
Studies
Life-Course Framework Reframes Type 2 Diabetes Prevention Before Dysglycemia Sets In
The conventional approach to type 2 diabetes prevention — intervening once blood sugar is already trending abnormal…
Nutrition
Review Identifies Six Molecular Pathways Linking Gut Microbiota to Immune Programming
Understanding precisely how the gut microbiome shapes immunity—not just that it does—is now one of the most…
Studies
CDK9 Inhibition Targets Transcriptional Addiction in Blood Cancers
For patients with blood cancers that resist standard therapies, the challenge has long been that malignant cells…
Studies
Phase 3 Trial: Obinutuzumab β Cuts NMOSD Relapse Risk by 93%
For people living with neuromyelitis optica spectrum disorder — a devastating autoimmune condition that attacks the…
Longevity
Blood Stem Cell Aging Mechanisms Reveal Promising Rejuvenation Pathways
The blood system is quietly central to how we age. Hematopoietic stem cells (HSCs) orchestrate lifelong immune…
Studies
CFTR Modulator Pharmacokinetics Shift Significantly in Pediatric Liver Disease
For children with cystic fibrosis who also develop advanced liver disease, treatment options narrow considerably — and…
Studies
66 Radionuclide-Drug Conjugates Mapped for Lung Cancer Precision Targeting
Lung cancer kills more people annually than any other malignancy, and the persistence of drug resistance alongside…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.