Longevity
Gut Bacteria Species Linked to Faster or Slower Epigenetic Aging Pace
The speed at which a person biologically ages may be partially written in the bacteria living in their gut — a…
Studies
Spatial QSP Model Links Fibroblast Density to HCC Immunotherapy Response Variation
Understanding why immunotherapy succeeds in some liver cancer patients but fails in others has been one of oncology's…
Studies
São Paulo Pediatric Leukemia Deaths Fell 28% Over Two Decades
Declining childhood cancer mortality is one of oncology's genuine success stories, yet the pace of progress varies…
Studies
Psoriasis Patients Show Nearly 3x Higher Myocardial Dysfunction Rate Independent of Risk Factors
The cardiovascular risk carried by psoriasis has long been attributed to shared inflammatory pathways and…
Studies
Epigenetic Chromatin Fixation Explains Why Checkpoint Inhibitors Incompletely Reverse T Cell Exhaustion
For the millions of cancer patients who respond only partially — or not at all — to checkpoint immunotherapy, a…
Studies
PPAR Agonists Elafibranor and Seladelpar Reframe PBC Treatment Beyond First-Line Therapy
For the roughly 40% of primary biliary cholangitis patients who fail ursodeoxycholic acid — the standard first-line…
Studies
Triclosan Analogue PA74 Revives Polymyxin Against Resistant Gram-Negative Bacteria
Antibiotic resistance among Gram-negative pathogens has pushed polymyxins — drugs of last resort — into frontline use…
Studies
Male Sex Linked to Better EMS Stroke Recognition but Worse Survival Outcomes
Stroke remains one of the most time-sensitive medical emergencies, where minutes between symptom onset and treatment…
Longevity
Acid Ceramidase Links Senescent Cell Lipid Metabolism to Ferroptosis Vulnerability
Selectively eliminating senescent cells — the so-called "zombie cells" that accumulate with age and drive chronic…
Studies
Novel Boron-Based Compound Defeats Ceftriaxone-Resistant Gonorrhea in Animal Models
With gonorrhea inching toward untreatable status, the discovery of a mechanistically distinct compound that bypasses…
Studies
CSF Liquid Biopsy Detects Pediatric Brain Tumor DNA With 54% Success Rate
For children diagnosed with brain tumors, tissue biopsies carry serious neurological risk — yet without molecular…
Studies
Global Mental Disorder Burden Mapped Across 204 Nations Over Three Decades
Mental illness remains one of the most underestimated contributors to global disability, yet rigorous cross-national…
Studies
RNA Methylation Regulators Emerge as Precision Targets in Heart Disease
For decades, cardiovascular research focused on DNA mutations and protein-level changes. A quieter revolution has been…
Studies
Prenatal Cannabis and Opioid Exposure Linked to Lower Birth Weight in HBCD Cohort
Birth weight is one of the strongest early predictors of infant health trajectories, making any modifiable contributor…
Studies
Neuroinflammation Linked to Small Vessel Disease but Causality Remains Unproven
Vascular dementia is frequently dismissed as the less-glamorous sibling of Alzheimer's disease, yet cerebral small…
Wellbeing
Aspirin Reverses Diet-Induced Depression in Mice via Arachidonic Acid Pathway
The possibility that a common over-the-counter drug could interrupt a dietary pathway leading to depression reframes…
Studies
Blood RNA Instability in 85% of Genes Challenges Transcriptomic Biomarker Reliability
For clinicians and researchers betting on blood-based RNA signatures to diagnose or monitor disease, a fundamental…
Studies
DRC Mineral Extraction Tied to Zoonotic Spillover and Planetary Health Risks
The intersection of resource extraction, ecosystem disruption, and infectious disease emergence is rarely captured in…
Studies
Vebreltinib Outpaces Crizotinib in MET-Mutant Lung Cancer With 8.7-Month PFS
For the roughly 1–3% of non-small cell lung cancer patients harboring MET exon 14 skipping mutations, treatment…
Nutrition
Gut Jet Lag: Exploring How Trans-Meridian Travel May Affect Microbiota and Athletic Performance
For elite athletes competing across multiple time zones, the performance gap may not be training or nutrition — it may…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.