Microglial Metabolic Reprogramming Sustains Neuroinflammation via Self-Reinforcing Signalling Cycles
Understanding why neuroinflammation persists long after its initial trigger — and why it selectively devastates aging…
Understanding why neuroinflammation persists long after its initial trigger — and why it selectively devastates aging…
Hidradenitis suppurativa—a painful, disfiguring inflammatory skin disease marked by recurring abscesses and sinus…
The landscape of pharmacological obesity treatment has undergone a fundamental transformation in recent years, and…
Chronic low-grade inflammation — inflammaging — is one of the most potent drivers of age-related disease, yet its…
The ability to identify Alzheimer's disease years before cognitive decline becomes apparent has long been considered…
Fatty liver disease has long lacked effective pharmacological options, leaving millions of patients with progressive…
Road injuries remain one of the most preventable sources of premature death and disability on the planet, yet progress…
Among 8,394 STEMI patients treated with PCI across four Israeli academic centers (2016–2023), those presenting with…
Among 764 HFpEF patients without pre-existing atrial fibrillation followed for a median 5.81 years in a Hong Kong…
In a retrospective cohort of 22,812 surgical patients with 159,782 simultaneous blood pressure measurement pairs…
A UK Biobank genome-wide association study identified distinct genetic loci across three rare but deadly…
Among 553,519 skilled nursing facility (SNF) residents with documented hypertension diagnoses drawn from over 1.28…
Locally applied lipid nanoparticle (LNP)-encapsulated hepatocyte growth factor (HGF) mRNA, delivered directly to…
Among 764 participants in the community-based Xiangya Osteoarthritis Study, the 52 with symptomatic hand…
Cellular aging shifts intercellular signaling from coordinated, functional communication toward chaotic, inflammatory…
As GLP-1 receptor agonists become among the most prescribed medications globally — used not just for diabetes and…
Dementia caregiving is among the most psychologically demanding roles a person can take on, yet evidence-based mental…
Knee osteoarthritis affects tens of millions of adults globally, and the dominant clinical assumption has long been…
For the millions living with Parkinson's disease, cognitive decline is one of the most feared complications — yet its…
For patients with multiple myeloma who have exhausted standard treatment options, the immunotherapy landscape is…
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