Studies
Triple Hormone Agonist Retatrutide Cuts HbA1c and Weight in Phase 3 Trial
For the millions of adults managing early type 2 diabetes through diet and exercise alone, the therapeutic window…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB and HIV Progress Assessed
Tuberculosis remains one of the most consequential infectious disease burdens on the planet, yet its trajectory — and…
Studies
Antibodies Targeting TβRI Cleavage Inhibit Androgen-Independent Prostate Cancer Growth and Metastasis in Preclinical Models
For men whose prostate cancer has outrun hormone therapy, treatment options narrow sharply and survival odds remain…
Studies
Follistatin-IGF1R Signaling Axis Identified as Driver of Chronic Facial Pain
Trigeminal neuropathic pain — the severe, often treatment-resistant facial pain affecting millions worldwide — has…
Supplements
Spermidine Reverses B-Cell Senescence, Rescues COVID Vaccine Response in Elderly Non-Responders
Vaccine failure in older adults is not random — it may be biologically predictable and, critically, potentially…
Studies
Synthetic Cannabinoids Block Key Cardiac Ion Channel Linked to Fatal Arrhythmia
The rising global use of synthetic cannabinoids — marketed as legal alternatives to cannabis — has been accompanied by…
Longevity
PINK1-Phosphorylated Ubiquitin Emerges as Central Signal in Mitochondrial Disease Pathways
Understanding why neurons and heart cells die prematurely in neurodegenerative and cardiometabolic diseases may hinge…
Studies
iPSC Neural Stem Cell Transplant Clears Phase 1 Safety Bar in Spinal Cord Injury
For the millions living with paralysis from spinal cord injury — a condition medicine has long considered largely…
Studies
Personalized Gene-Silencing Therapy Cuts Seizures in SCN2A Epilepsy Patients
For families living with treatment-resistant childhood epilepsy, the prospect of a therapy designed specifically…
Studies
Qdenga Dengue Vaccine Triggers Tetravalent Response in Only 8% of Naïve Adults
For a vaccine marketed as tetravalent protection against all four dengue serotypes, the actual breadth of immune…
Wellbeing
Accountability-Embracing Science Communication Rebuilds Conservative Trust Post-Pandemic
How scientists talk about their own mistakes may matter as much as the science itself — particularly for audiences who…
Studies
Pre-existing Anti-Interferon Autoantibodies Linked to Life-Threatening COVID-19 Severity
Understanding why a subset of otherwise healthy individuals develops catastrophic viral pneumonia while others recover…
Studies
ACS 2026 Guidelines Add Three New Molecular CRC Screening Tests
Colorectal cancer mortality is increasingly a problem for adults under 65 — a demographic once considered relatively…
Studies
Global Mental Disorder Burden Rose Sharply Over Three Decades, GBD 2023 Finds
Mental health has quietly become one of the defining public health crises of our era — not because the science has…
Studies
Human-Specific RNA Molecule Controls Macrophage Survival During Bacterial Infection
The line between surviving an infection and succumbing to it may partly hinge on a single RNA molecule most…
Studies
B Cell Antibody Responses in Lymph Nodes Drive CTLA-4 Glioma Therapy
Brain cancer immunotherapy has long been assumed to succeed or fail based on T cell activity within tumors — a…
Studies
Hospital-Acquired Infections Drop 27% Between 2015 and 2023 Surveys
Nearly half a million Americans still acquire an infection during a hospital stay each year — a figure that demands…
Studies
Schistosoma Infection Alters COVID Vaccine Immunity But Not Protection in Mice
For the roughly two billion people living in helminth-endemic regions — much of sub-Saharan Africa, South Asia, and…
PREPRINTStudies
5-Point Imaging Score Predicts 50% Complication Rate in High-Risk Bicuspid TAVI
A newly developed five-indicator anatomic score, derived from routine preprocedural CT and echocardiography, predicts…
PREPRINTLongevity
South Asian Women Show 2.4× Higher CHD Hazard vs European Women in SABRE Cohort, with Attenuated Sex Difference
A 40.8-year follow-up of 4,754 participants in the SABRE tri-ethnic UK cohort found stark sex-by-ethnicity disparities…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.