Supplements
GLP-1 Agonists and Diet Shrink Heart Fat Beyond Weight Loss Alone
A multilevel meta-regression of 42 interventional studies (50 arms, 1,890 participants) found that BMI reduction…
Studies
Ampyrone Activates Human Tyrosinase, Opening Door for Albinism Treatment
For the roughly 1 in 17,000 people born with oculocutaneous albinism and millions more affected by acquired…
Studies
Vibration Device Plus Video Games Cut Vaccine Fainting Risk 25% in Teens
Fainting and near-fainting after routine vaccinations are among the most disruptive events in adolescent clinical care…
Wellbeing
Live Sports Spectatorship Linked to Heart-Rate Synchrony and Endogenous Oxytocin Dynamics
The persistent failure of intranasal oxytocin trials to reliably improve social functioning has pushed researchers…
Studies
Nirsevimab Cuts Infant RSV Hospitalizations Across Two Consecutive Seasons
Most infant immunization data stops at one season — making it genuinely difficult to judge whether protective effects…
Studies
Enteric Infectious Diseases Cause 1.27 Million Deaths in 2023, Down from 3.69 Million in 1990, but 2025 GAPPD Target Elusive
More than a million deaths annually from gut infections may sound like a historical relic in an era of vaccines and…
PREPRINTLongevity
3,029 Mexican CCS Patients Show 74% Miss LDL Targets Despite 93% Statin Use
Among 3,029 Mexican adults with chronic coronary syndrome (CCS) enrolled across ~50 centers between September 2024 and…
PREPRINTLongevity
Explainable ML Model Achieves AUC 0.84 for Post-Discharge Heart Failure Mortality Prediction in 3,933-Patient Preprint
Among 3,933 heart failure patients discharged from New South Wales hospitals, 45.2% experienced emergency readmission…
PREPRINTLongevity
Drug-Coated Devices Associated With 86% Higher Wound Healing Rate in Observational CLTI Study
Among 341 consecutive patients with chronic limb-threatening ischemia (CLTI) undergoing infrainguinal endovascular…
PREPRINTStudies
Low-Volume TAVR Hospitals Linked to ~10% Higher Adjusted Odds of 1-Year Mortality in 215,000 Medicare Patients
Among 215,335 Medicare patients undergoing transcatheter aortic valve replacement (TAVR) across 788 U.S. hospitals…
PREPRINTLongevity
Wrist Device Tracks Heart Failure Decongestion with 0.85 AUC Readmission Signal
A wrist-worn, machine-learning device analyzing venous waveforms — the NIVAHF device — produced a non-invasive…
Studies
Fluvoxamine Cuts Long COVID Fatigue Scores in 399-Patient Randomized Trial
For millions of adults still grappling with crushing fatigue months after a COVID-19 infection, the absence of proven…
Studies
Cancer Survivors and Oncology Providers Diverge Sharply on Cannabis Risk Awareness
When patients and their oncologists hold fundamentally different assumptions about the same therapy, clinical…
Studies
Itch-Sensing GPCR MRGPRX4 Identified as Potent Melanoma Driver and Therapy Target
Melanoma's notorious resistance to therapy often traces back to poorly understood dedifferentiation programs — the…
Nutrition
GLP-1 Agonists and Bariatric Surgery Cut Uric Acid, Reframe Gout Treatment
Excess adiposity causally elevates serum uric acid (SUA) through at least four converging mechanisms: insulin…
Longevity
Review Maps Microplastics-Gut Microbiome Links to Aging Pathways Including TLR4/NF-κB
Micro- and nanoplastics (MNPs) enter the human body through oral ingestion, inhalation, and dermal absorption, and…
Longevity
Manganese Overload Triggers Cellular Senescence via STING; Quercetin Reverses Damage
Excess manganese (Mn) — encountered occupationally in welding, mining, and battery manufacturing — drives cellular…
Nutrition
Time-Restricted Eating for Fatty Liver May Erode Muscle, Trigger Rebound Weight Gain
For the millions managing metabolic fatty liver disease, intermittent fasting and calorie restriction have emerged as…
Studies
XGBoost Model Uses Clinical Notes to Forecast Pediatric Asthma Attacks
Childhood asthma remains one of the most burdensome chronic conditions in pediatrics, yet clinicians still lack…
Studies
Central Harlem Legionnaires' Outbreak Traced to Two Cooling Towers via Genomic Sequencing
Urban water infrastructure remains one of the most underappreciated public health threats for city dwellers — and a…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.