Longevity
Green Space Linked to 13% Lower CVD Odds, But NO2 May Attenuate the Benefit
Where someone lives may matter as much as how they live. The simultaneous pull of urban greenery and urban air…
Studies
Digital Vaccination Apps Linked to Reduced HPV Vaccine Hesitancy Among Texas Patients
HPV vaccination rates remain stubbornly low in parts of the United States, and the COVID-19 pandemic accelerated…
Studies
Two Blood Biomarkers Outperform Eosinophil Counts in Pediatric Allergy Diagnosis
Diagnosing allergic rhinitis in children relies heavily on clinical symptoms and skin-prick tests, but objective blood…
Wellbeing
EEG Reveals Two-Stage Neural Breakdown in Autistic Children's Audiovisual Speech
How the brain stitches together what eyes see and ears hear during speech is a capability most people take for granted…
Studies
Congo Basin Conflict and Mineral Extraction Linked to Heightened Zoonotic Spillover Risks Involving at Least 15 Pathogens
The intersection of armed conflict, mineral extraction, and tropical biodiversity makes the Congo Basin one of the…
Studies
Vape Puffing Governed by Mouth Sensation, Not Brain Nicotine Signals
The assumption underpinning nicotine reduction policy—that smokers and vapers consciously or unconsciously adjust…
Studies
Bispecific ADC Targets EGFR/HER3 in Treatment-Resistant Prostate Cancer with Defined Resistance Mechanism
Metastatic castration-resistant prostate cancer carries one of oncology's bleakest prognoses, and the antibody-drug…
Studies
FL118 Degrades Two Cancer Proteins Simultaneously, Targeting Treatment-Resistant Tumors
For patients facing cancers that have exhausted standard treatment options — pancreatic adenocarcinoma, glioblastoma…
Studies
72% of Sri Lankan Children Carry Dengue Antibodies by Age 16
In regions where dengue is endemic, understanding exactly when children acquire immunity — and to which viral strains…
Studies
Recurrent Heart Attacks Carry Higher Mortality and Complication Burden Than First Events
Surviving a heart attack no longer means the danger has passed — it increasingly means a patient enters a higher-risk…
Studies
CDK4/6 Inhibitor Evolution: Resistance Mechanisms Drive Next-Generation Cancer Therapies
A decade after the first FDA approval of CDK4/6 inhibitors, oncology stands at a meaningful inflection point — one…
Fitness
Semaglutide + Exercise Cuts Fat 45%, Partially Saves Muscle via Mitochondrial Pathways
In diet-induced obese Ldlr-/-.Leiden mice over 14 weeks, semaglutide alone reduced fat mass by 31% but also trimmed…
Supplements
GLP-1RA Dual Agonists May Elevate Fracture Risk; Urine DPD Biomarker Offers Early Warning
GLP-1 receptor agonist monotherapy appears largely bone-neutral, but dual agonists — such as tirzepatide targeting…
Nutrition
200–300 MPa Pressure Boosts Resveratrol Bioactivity and Enzyme Inhibition in 2 Minutes
Applying high-pressure processing (HPP) at 200–300 MPa for just 2 minutes measurably increased resveratrol content and…
Nutrition
Lutein & Zeaxanthin Lead Ocular Nutraceuticals; Curcumin, Resveratrol Lag Behind
Among all food-derived bioactive compounds examined for ocular disease, lutein and zeaxanthin stand out as the only…
Longevity
Lipid-Rich Microglia Correlate with Hippocampal Memory Decline in Middle-Aged Rats
In middle-aged rats, hippocampal microglia adopted a lipid-rich, pro-inflammatory phenotype that correlated directly…
Longevity
GDF15 and Activin A Emerge as Cross-Domain Senescence Biomarkers Linking 4 Age-Related Disease Categories
A comprehensive NIH-authored compendium identifies circulating senescence-associated secretory phenotype (SASP)…
Supplements
Piceatannol Cuts IGFBP4/5/7 Senescence Signals, Improves Memory in Aging Mice
Oral piceatannol (PCT), a stilbene and direct resveratrol metabolite with superior bioavailability, demonstrably…
Longevity
Irisin Links Muscle Contraction to Alzheimer's Protection via Brain Signaling
With Alzheimer's disease cases in the U.S. projected to more than double to 14 million by 2060, the search for…
Longevity
Accelerated Biological Aging Linked to Rising Early-Onset Cancer Risk Across Generations
Early-onset cancer — diagnosed before age 50 — has been climbing globally for decades, and the explanation has…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.