Studies
Pancreatic Ductal Cells Acquire Immune-Presenting Function Under Inflammatory Cytokine Exposure
Understanding how type 1 diabetes progresses beyond beta-cell destruction could reshape therapeutic targeting — and a…
Longevity
100-Year Bibliometric Analysis Maps Caffeine, Polyphenols, and Gut Microbiota as Core Alzheimer's Research Themes
A structured bibliometric sweep of 2,873 Scopus-indexed articles spanning 1911–2025 maps how coffee and tea research…
Longevity
uPAR-Targeted Nanoparticles Deliver Dasatinib+Quercetin to Clear Senescent Fat Cells
Co-encapsulating dasatinib and quercetin — the canonical D+Q senolytic combination — into uPAR-targeted hybrid…
Longevity
Senolytic Drugs Reverse Aged Microglia Buildup in Brain White Matter
In naturally aged mice, a previously uncharacterized microglial population accumulates specifically in…
Supplements
Ergothioneine Restores Aging Circadian Clocks via NAD+ Redox Rescue
Ergothioneine (EGT), a sulfur-containing amino acid found in mushrooms and certain bacteria, dose-dependently restored…
Studies
GLP-1 Users Report 'Food Noise' Reduction, Cite Need for Ongoing Support and Lifestyle Changes
Understanding why patients stop a medication that works — and then rapidly regain what they lost — is one of the most…
Studies
Phase 3 Semaglutide Trials Find No Cognitive Benefit in Early Alzheimer's
The hypothesis that GLP-1 receptor agonists could slow Alzheimer's progression was among the most watched bets in…
Studies
Vitamin K Refusal at Birth Linked to Higher Infant Bleeding Risk in 2M Cohort
A preventable cause of infant brain damage and death has quietly gained ground as parental refusal of a standard…
Longevity
Semaglutide Cuts Epigenetic Age by Up to 4.9 Years in Randomized Trial
The possibility that a widely prescribed metabolic drug might also slow biological aging has moved meaningfully closer…
Longevity
Semaglutide Cuts Biological Age by Up to 4.9 Years in Controlled Trial
For decades, the quest for a drug that measurably slows biological aging has remained elusive. Evidence from a…
Studies
Updated FDA Method Detects Five Cyclospora Oocysts in Outbreak-Linked Produce
Foodborne illness from fresh produce remains one of the more difficult public health challenges to trace and prevent…
Studies
New Functional Vision Tool Shows Strong Reliability for Pediatric CVI Trials
Cerebral visual impairment remains one of the most underdiagnosed and poorly measured conditions affecting children's…
Studies
AUTAC-Lysosome Strategy Synergizes With Proteasome Inhibitors to Overcome Cancer Drug Resistance
One of the most stubborn problems in oncology is cancer cells that learn to survive the very drugs designed to kill…
Studies
AI Outperforms Traditional Tests in Predicting Difficult Airways, With Caveats
Airway management failures remain among the most consequential events in anesthesia and emergency medicine — and…
Studies
Once-Daily iTBS Brain Stimulation Outperforms Sham in Randomized Depression Trial
For the millions of adults with major depressive disorder who achieve inadequate relief from medication, non-invasive…
Nutrition
Chronic Xanthan Gum Intake Triggers Colon Inflammation and Microbiota Shifts in Rats
Xanthan gum appears in ingredient lists across thousands of packaged foods, gluten-free products, and clinical…
Studies
KRAS Inhibitors Show Potent Preclinical and Clinical Activity in Rare Appendiceal Cancer
Appendiceal adenocarcinoma is one of oncology's orphan diseases — so rare that standard chemotherapy regimens borrowed…
Nutrition
Sarcopenia and Type 2 Diabetes Share Bidirectional Molecular Pathways Accelerating Muscle Loss
For aging adults managing blood sugar, muscle loss is not merely a side effect — it may be an active accelerant of…
Studies
Transcription Factor Drug Targeting: Why Cancer's 'Undruggable' Proteins May Yield
For decades, the proteins that control which genes get switched on or off inside cancer cells were considered…
Studies
Gestational Hypertension Linked to 3.5-Fold Higher Long-Term Hypertension Risk in 15-Year Cohort Study
For women who have experienced complications during pregnancy, the cardiovascular consequences can extend far beyond…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.