Wellbeing
AI Chatbots Amplify Psychological Vulnerabilities in 810-Conversation Mental Health Audit
As AI chatbots become de facto mental health resources for millions who lack access to licensed therapists…
Wellbeing
Wearable Ultrasound Patch Boosts REM Sleep 4.6% via Non-Invasive Deep Brain Stimulation
The ability to modulate deep brain structures without surgery has long been a holy grail for neuroscience and sleep…
Studies
Whole-Genome Study Links Parental Age and IVF to De Novo Mutation Rates
Every human genome carries a small number of mutations that appeared for the first time in that individual — not…
Studies
New ICD Code Reveals Cannabis Hyperemesis Syndrome Is 3.7× More Common Than Recorded
A condition long hidden beneath vague diagnostic codes is finally surfacing in emergency data — and its true burden…
Studies
Cook County Measles Cluster Reveals ED Waiting Rooms as Transmission Hotspots
When measles resurfaces in a vaccinated population, the details of exactly how it spreads matter enormously — and this…
PREPRINTLongevity
BD-p-tau217 Predicts Brain Amyloid, But Kidney Disease Weakens Signal
In 541 cognitively unimpaired, late middle-aged Hispanic, non-Hispanic Black, and non-Hispanic White adults…
PREPRINTLongevity
Childhood Poverty Associated with Higher Allostatic Load in Later Life—But Only in 3 of 6 Nations
Across six harmonized longitudinal aging cohorts totaling over 23,000 adults (mean age ~65), early-life…
PREPRINTWellbeing
Depression Linked to 49% Higher Mortality Risk in 297 Haemodialysis Patients
Among 297 adults receiving maintenance haemodialysis in North and East London, moderate-to-severe depressive…
PREPRINTLongevity
CRISPR Validation Links Liver Protein ITIH4 to Cholesterol in 640,000-Person Proteome Map
Genetic imputation models for 2,594 plasma proteins — built from 54,219 UK Biobank participants — were projected onto…
PREPRINTWellbeing
Weekly Dance Classes Linked to Stable Insomnia and Cognitive Trends vs. Decline in Parkinson's Over 6 Years
Over six years, people with Parkinson's disease (PwPD) attending weekly community-based dance classes showed…
Supplements
GLP-1 Weight Loss Includes 25–39% Lean Mass Loss, Similar to Diet: CKM Patients Face Sarcopenia Risk
Across incretin-based therapies — GLP-1 receptor agonists and dual GLP-1/GIP agonists like semaglutide and tirzepatide…
Supplements
30B CFU Daily Probiotic Boosts Happiness 12.7%, Cuts IL-6 20% in Older Adults
Eight weeks of daily supplementation with 30 billion CFU of Pediococcus acidilactici PA53 in 75 adults aged 55–70…
Longevity
Senolytics, Epigenetic Reprogramming, and AI Converge in Precision Longevity Medicine
The boundary between aging and disease is dissolving faster than most clinicians appreciate. A comprehensive review in…
Studies
Non-Coding DNA Deletions Reduce FOXG1 Expression, Expanding Neurodevelopmental Disorder Mechanisms
Most genetic explanations for neurodevelopmental disorders focus on mutations that directly damage protein-coding…
Studies
Endosomal Calcium Channel TPC1 Controls Iron Homeostasis via Receptor Trafficking
Iron deficiency remains one of the most prevalent nutritional disorders globally, yet its cellular regulation is still…
Wellbeing
Night Shift Work Linked to 88% Higher Long-COVID Risk, Insomnia Compounds It Further
Long-COVID remains one of the most poorly understood sequelae of SARS-CoV-2 infection, and identifying modifiable risk…
Studies
Heat and Bushfire Smoke Associated with Higher Cardiovascular, Respiratory, and Mental Health Service Use in Australia
Climate-driven exposures are no longer theoretical health risks — they are measurable, quantifiable burdens already…
Wellbeing
Depression Linked to Specific Hippocampal Shrinkage, Independent of Alzheimer's Pathology
The intersection of mood disorders and dementia risk is one of the most consequential puzzles in aging neuroscience…
Longevity
Human Hippocampus Undergoes Sweeping Epigenetic Reorganization Between Ages 50–75
The decades between 50 and 75 may be far more biologically eventful in the brain than previously appreciated — not…
Fitness
Endocannabinoid System Identified as Central Coordinator of Runner's High Neuroscience
For decades, the euphoria and pain relief that follow sustained aerobic exercise have been dismissed as a simple…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.