Longevity
Resveratrol Extends Female Drosophila Lifespan Across 2 Generations via H3K9ac Epigenetic Rewriting
At 50 μg/ml, resveratrol produced sharply divergent outcomes depending on timing: embryonic exposure accelerated…
Studies
THC+CBD+Nicotine Triggers Fetal Lung Senescence Reversed by Dasatinib-Quercetin
Combined exposure to THC, CBD, and nicotine in human fetal lung explants (10–16 weeks gestation) suppresses…
Nutrition
Gut Microbiota Orchestrates Vitamin A Routing to Program Intestinal Immunity
The relationship between what we eat and how our immune system develops has long been assumed to be largely direct…
Studies
Quadruple pegRNA System Achieves 40% Efficiency for Large Gene Insertions
A persistent bottleneck in gene therapy has been the inability to insert large, therapeutically meaningful stretches…
Studies
GPR173 Gene Therapy Curbs Drug-Resistant Epilepsy via GABA Receptor Boost
For the roughly one-third of epilepsy patients whose seizures resist every available medication, the search for…
Studies
Cryo-EM Structures Reveal How Cebranopadol Binds Two Pain-Relief Receptors Simultaneously
Understanding exactly how next-generation analgesics interact with their molecular targets could reshape opioid…
Studies
Odoroside A Disrupts Fat Metabolism Pathway to Suppress Colorectal Cancer Cells
Colorectal cancer's stubborn lethality stems partly from how tumor cells hijack lipid metabolism to fuel their own…
Studies
Weight-Loss RCTs Rarely Address Psychological Factors Linked to Eating Disorder Risk
Most adults pursuing structured weight loss assume the programs they enroll in have been designed with safety…
Studies
Chikungunya Clinical Overview: Transmission, Diagnosis, and Prevention Examined
Mosquito-borne viral diseases are expanding their geographic reach, and chikungunya — long considered a pathogen of…
Nutrition
Daily Yogurt Intake Linked to Higher Essential Nutrient Density Across All Ages
As plant-based food guidance reshapes national dietary recommendations, a critical question emerges: are dairy…
Longevity
Gut Metabolite ImP Accelerates Tau Pathology and Blood-Brain Barrier Breakdown
A compound most people have never heard of — produced quietly in the gut by certain bacteria — may be quietly…
Studies
Cancer Drug Toxicity Tracking Lags Behind Survival Gains in Oncology
As cancer survival rates climb to historic highs, a growing population of long-term survivors is living with side…
Studies
2025 Tau Global Conference Maps Biomarker and Therapeutic Frontiers in Tauopathies
Tau protein dysfunction underlies not just Alzheimer's disease but a spectrum of devastating neurodegenerative…
Studies
CGM Tight-Range Metrics Detect Prediabetes Risk in Obese Youth
Standard blood glucose screening tools were designed largely around adult physiology, yet the pediatric obesity…
Studies
TB Burden Declines Substantially Since 1990 per GBD 2023, But MDR-TB Progress Lags
Tuberculosis remains the world's deadliest infectious disease from a single pathogen, yet most people lack a current…
Nutrition
Time-Restricted Eating Lowers Blood Pressure 4mmHg But Metabolic Gains Remain Modest
For millions of adults drawn to intermittent fasting as a metabolic reset, a rigorous review of the clinical trial…
Studies
Network Meta-Analysis Ranks GLP-1 Agonists by Composite Cardiometabolic Benefit Across 13,000 Adults
With GLP-1 receptor agonists now crowding the market in both injectable and oral forms, clinicians and patients face a…
PREPRINTStudies
Elevated NLR Associated With 60% Higher Pericarditis Mortality Risk in Two Independent Cohorts
In 968 hospitalized pericarditis patients drawn from two independent databases — a Hong Kong CDARS cohort (n=504) and…
PREPRINTStudies
10-Year Registry: Troponin Testing Surged 69% While MI Hospitalization Dropped 36%
Across 117,142 consecutive emergency department presentations in Scotland's Lothian region between 2014 and 2024…
PREPRINTLongevity
Triple Antihypertensives Cut Systolic BP 5.4 mmHg More Than Dual Therapy in 13,461-Patient Meta-Analysis
Across 17 double-blind randomized trials encompassing 13,461 adults with hypertension, triple antihypertensive drug…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.