PREPRINTLongevity
AI Reads Heart Ultrasounds to Detect Hidden Kidney Disease in 850M-Patient Crisis
A deep learning model trained on 325,377 echocardiography videos from 62,818 patients at Cedars-Sinai can detect…
PREPRINTStudies
BiLID Index Predicts Cardiac Muscle Damage Better Than Application Count in PFA Ablation
A retrospective analysis of 1,556 pulsed-field ablation (PFA) applications in 23 patients undergoing pulmonary vein…
PREPRINTStudies
4.2% of Children Show Persistent High BP, Yet Only 1.2% Diagnosed
Among 71,683 children aged 6–17 tracked across three or more primary care visits from 2017–2024, 4.2% (2,911)…
PREPRINTLongevity
AI Segments Heart Fat Depot in 60 Seconds vs. 58-Minute Manual Process
A deep-learning pipeline using nnU-Net architecture trained on 165 cardiac MRI cases achieved automated segmentation…
PREPRINTStudies
HeartBioPortal 3.0 Integrates 594M Allele Observations Into Single Cardiovascular Genomics Hub
HeartBioPortal 3.0 (HBP 3.0) consolidates cardiovascular genomic intelligence into a single browser-based environment…
Supplements
High-Dose DHA Crosses Blood-Brain Barrier in At-Risk Adults, APOE Status Irrelevant
For the millions of adults carrying the APOE ε4 gene variant — the single largest genetic risk factor for Alzheimer's…
Studies
Dual Adjuvant Therapy Cuts Kidney Cancer Recurrence Risk by 28%
For the roughly 400,000 people diagnosed globally each year with kidney cancer, the post-surgical window represents…
Fitness
16-Week Exercise Cuts HIV-Related Frailty 37% in Adults Over 50
Among 94 older adults with HIV who completed a 16-week randomized exercise trial, pre-frailty and frailty prevalence…
Longevity
Review Proposes Four Aging Hallmarks Form Self-Reinforcing Network in AMD, Glaucoma, Diabetic Retinopathy
Four molecular hallmarks — mitochondrial dysfunction, loss of proteostasis, cellular senescence, and epigenetic drift…
Studies
TBI in Older Veterans Reveals Bidirectional Links to Dementia, Stroke, Parkinson's
The conventional view of traumatic brain injury as a trigger for neurological decline may be only half the story. For…
Studies
40% of UK Emergency Admissions Could Be Managed as Same-Day Outpatient Care
For health systems straining under the weight of aging populations, the question of which hospital admissions are…
Studies
Letrozole Upgrades Sperm Concentration in 3-Month Trial of Severe Male Infertility
Male infertility affects roughly one in six couples worldwide, yet evidence-based treatments for the most severe forms…
Studies
Visible Light Rewires Immune Cells Against Tumors Through Melanopsin Epigenetics
The idea that ordinary visible light could reshape the immune system's cancer-fighting capacity sounds…
Longevity
Aging Muscle Exports miR-125a-5p Vesicles That Silence Bone Formation
The long-held assumption that sarcopenia and osteoporosis simply co-occur with age may need revision. New mechanistic…
Studies
RNA m6A Methylation Writers Emerge as Targets for Autoimmune Disease Therapy
A largely invisible layer of gene regulation — not the DNA sequence itself but chemical tags on RNA — may hold the key…
Studies
RNA Methylation Activates Triple-Death Pathway in Sepsis Heart Damage
Understanding why the heart fails during severe infection has long eluded critical care medicine. A newly identified…
Longevity
Centenarian Gene Variant Linked to Platelet CD47 Changes Associated with Suppressed Aging-Related Inflammation
Understanding why some people reach 100 in robust health while others decline decades earlier is one of longevity…
Studies
Upadacitinib Outperforms TNF Inhibitors in Real-World RA Treatment Persistence
For the roughly 1.3 million Americans living with rheumatoid arthritis, choosing between newer JAK inhibitors and…
Studies
Pain-Sensing Nerves Suppress Anti-Tumor Immunity in Lung Cancer Via CGRP
Most cancer immunology research focuses on T cells, checkpoint inhibitors, and tumor mutational burden — but the…
Studies
Germline-Targeting HIV Vaccine Elicits Broad Neutralizing Antibodies in Primates
For four decades, HIV's extraordinary ability to mutate and diversify has defeated every conventional vaccine…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.