PREPRINTStudies
Self-Supervised AI Cuts Cardiac Oxygen Error 15% Without Invasive Catheterization
A self-supervised learning (SSL) framework trained on over 48,000 cardiac MRI images achieved a mean absolute error of…
Studies
Gut Microbiome Links to Polyphenol Metabolites: 56-Study Scoping Review Maps Associations and Evidence Gaps
Across 56 human clinical studies, the relationships between gut microbiota and microbial-derived polyphenol…
Longevity
Multilingualism Associated with Lower Loneliness in Aging via Anterior Temporal Lobe Gray Matter Mediation
Loneliness among older adults has emerged as one of the most consequential public health threats of our time…
Studies
Reproductive Aging After 35: Oocyte Quality, Paternal DNA, and ART Limits
For adults navigating family planning timelines, the biology of reproductive aging rarely matches the social narrative…
Studies
Review: Low-Intensity Ultrasound May Promote Neuronal Regeneration in Neurodegenerative Diseases
For the millions living with Alzheimer's, Parkinson's, or ALS, the absence of any therapy that meaningfully slows…
Studies
Single Antiviral Compound Blocks Multiple Coronavirus Strains Including SARS-CoV-2 Variants
The dream of a single antiviral that works across an entire family of pathogens — not just one strain — has long…
Wellbeing
Ultrasound Pulses Stimulate Deep Brain Repair Without Surgery or Implants
For the millions living with Alzheimer's, Parkinson's, or ALS, the absence of any therapy that genuinely slows…
Studies
Mental Health Outweighs Specific Symptoms in Long COVID Work Recovery
For the millions still navigating life after COVID-19 infection, the question of when — or whether — to return to work…
Studies
Polygenic Risk Scores Could Reshape Glaucoma Detection Before Vision Loss Begins
For the estimated 80 million people living with glaucoma worldwide, the disease's cruelest feature is its silence…
Studies
Semaglutide Gains FDA Approval for Teens 12+: Safety Data Gaps Remain
Liraglutide and semaglutide have achieved FDA and EMA approval for adolescents aged 12 and older, demonstrating…
Studies
First KRAS G12D Protein Degrader Shows 36% Response Rate in Lung Cancer
For decades, KRAS mutations were considered undruggable — a frustrating reality given that KRAS G12D is the dominant…
PREPRINTLongevity
Regional Heart Wall Mapping Reveals Hidden CVD Risk in Women, 10.6% Score Jump
Cardiac MRI data from 1,789 adults across three European population cohorts (SHIP-TREND-0, SHIP-START-2, KORA-FF4)…
PREPRINTLongevity
Transdermal Clonidine Cuts Hyperkalemia Risk 52% vs. Spironolactone in Resistant Hypertension
In a retrospective analysis of 33,753 U.S. patients with resistant hypertension drawn from Merative MarketScan claims…
PREPRINTLongevity
Statins Show No Primary CVD Protection in 1,396 Lupus Patients Over 8,708 Person-Years
Among 1,396 patients with systemic lupus erythematosus (SLE) followed across 8,708 person-years, statin use failed to…
PREPRINTLongevity
Lp(a) Tracks Strongly From Age 7 Months—Girls Carry Higher Burden Through Adolescence
Analyzing 7,018 lipoprotein(a) measurements across 1,062 children at 10 age points — from 7 months to 15 years — the…
PREPRINTLongevity
Deep Learning ECG Model Links Prolonged QTc to 2.9x Higher Cardiovascular Event Risk
A deep learning framework trained on 11,330 expert-annotated ECG leads from 1,030 UK Biobank participants achieved…
Supplements
Curcumin & Resveratrol Dominate 33-Year Sports Phytotherapy Research Surge
A bibliometric sweep of 3,404 Web of Science records (1991–2024), narrowed to 368 qualifying publications, reveals…
Wellbeing
Wearable Sensors May Bridge UK Veterans' Mental Health Monitoring Gap
For the substantial population of veterans who disengage from conventional mental health services, continuous…
Supplements
Resveratrol Blocks AKT/mTOR/S6K Cascade to Reverse Neurogenic Bladder Fibrosis in Rats
In a rat model of neurogenic bladder (NB) created by bilateral L6-S1 spinal nerve transection, resveratrol…
Longevity
Gut Bacteria-Derived Phenylacetyl-Carnitine Associated with Aging and Cognitive Impairment in Alzheimer's Studies
A sweeping metabolomics atlas spanning 2,271 samples across multiple tissues from two AD transgenic mouse models (3xTg…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.