Longevity
Rhododendron Iridoids Extend C. elegans Lifespan 30.8%, Outperforming NMN
Two iridoid compounds isolated from Rhododendron pachypodum flowers — compound 5 (a newly characterized analogue) and…
Studies
CVD Kills 3 Million Annually in Europe With Stark Income-Based Mortality Gaps
Cardiovascular disease remains the single largest killer across Europe and neighboring nations, yet where you are…
PREPRINTLongevity
ML Analysis of 10,712 Patients Finds No Meaningful Benefit Heterogeneity in Intensive BP Control
Pooling data from two large-scale randomized controlled trials across 10,712 participants followed for up to three…
PREPRINTLongevity
Liver Fibrosis Score Predicts 2× Mortality Risk in 2,467 Primary Aldosteronism Patients
Among 2,467 patients with primary aldosteronism (PA) tracked in a multicenter retrospective cohort, those with a…
PREPRINTLongevity
Small-Artery Elasticity Predicts Heart Ejection Fraction in 991-Person Cohort
In a community-based Swedish cohort of 991 adults (mean age 51), non-invasive radial artery applanation tonometry…
PREPRINTLongevity
Early Finerenone After Acute MI Linked to 36% Lower Composite Mortality and Heart Failure Risk
In a propensity score-matched real-world analysis of 1,012 high-risk post-AMI patients (mean age 69, ~84% with type 2…
PREPRINTLongevity
15.7% of Repaired CHD Patients Had True Care Gaps; Serious Outcomes in 26.7% of Those Needing Post-Gap Intervention
Among 1,746 patients with surgically repaired congenital heart disease (CHD) treated at a tertiary center from…
Wellbeing
Snoring Vibrations Disrupt Muscle Mitochondria via Mechanosensing Pathways
Most people treat snoring as a nuisance rather than a biological stressor, but emerging mechanobiology research…
Studies
Tumor Cell Death Modes Reshape Immunity: ICD's Dual Role Explained
How a cancer cell dies turns out to matter enormously — not just for clearing the tumor, but for whether the immune…
Studies
Preterm Birth Leaves Lasting Marks on Teeth, Jaw, and Craniofacial Bone
For the millions of infants born preterm or underweight each year, surviving the neonatal unit is no longer the…
Nutrition
8-Hour Feeding Window Extends Male Mouse Lifespan 12%, Sex Differences Emerge
For anyone practicing intermittent fasting, the assumption has been that eating within a compressed daily window…
Longevity
Post-Menopausal Ovary Becomes Active Immune Organ, Influencing Whole-Body Aging
For decades, the ovary after menopause was considered a spent organ—biologically silent once its follicles were gone…
Studies
Seven DLBCL Proteogenotypes Reveal Hidden High-Risk Subtype Beyond Standard Markers
For patients diagnosed with diffuse large B cell lymphoma, standard molecular classification still leaves a…
Studies
Unacylated Ghrelin Preserves 70% Muscle Force in Cancer Cachexia Model
For the millions of cancer patients who lose dangerous amounts of muscle mass during treatment, cachexia represents…
Studies
Six-Month Stewardship Program Targets Drug-Resistant Bacteria Across Vietnamese Hospitals
Antibiotic resistance quietly reshaping hospital safety worldwide rarely receives the granular, pre-and-post…
Studies
14-Protein Blood Signature Predicts Lung Cancer Five Years Before Diagnosis
Early cancer interception—stopping a tumor before it becomes one—has long been hampered by the inability to identify…
Nutrition
Plant-Based Diets Linked to 5–7% Lower MACE Risk in 99,000-Person CKM Cohort Study
Across 99,064 participants drawn from the UK Biobank and NHANES (2005–2018), adherence to the Alternative…
Longevity
Stress Ages Blood Stem Cells Via Brain-Gut-Spermidine-Ferroptosis Cascade
Chronic psychological stress impairs hematopoietic stem cell (HSC) self-renewal and lymphoid differentiation by…
Longevity
PRMT Enzymes Act as Molecular Rheostats Governing Muscle-Aging Degeneration
Protein arginine methyltransferases (PRMTs) function as molecular rheostats that tip mitochondrial stress responses in…
Longevity
Rapamycin Reverses Brain Vascular Amyloid, Hemorrhage, and Memory Loss in AD Mice
In Tg2576 mice modeling Alzheimer's disease with cerebral amyloid angiopathy (CAA), mTOR hyperactivation drives…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.