PREPRINTWellbeing
Community Dementia Prevention Classes Show Cognitive Gains But No Disease Protection
A retrospective analysis of 578 individuals across three Japanese municipalities found that community-based dementia pr…
PREPRINTStudies
Resting Facial Expressions Show Distinct Patterns in Mild Cognitive Impairment
Analysis of facial expressions in 31 individuals with mild cognitive impairment (MCI) versus 14 healthy controls reveal…
PREPRINTWellbeing
Stellate Ganglion Modulation Alters Heart Arrhythmia Risk After Heart Attack
Computer simulations using 14 patient-specific heart models revealed that stellate ganglion modulation—stimulation of k…
PREPRINTStudies
CXCL10, GREM2 Proteins Predict Acute Myocarditis Severity in 103 Patients
Analysis of 103 acute myocarditis patients across two cohorts identified specific protein signatures that predict disea…
PREPRINTStudies
Heart Guidelines Miss Mark: Only 6% Reach Surgery Thresholds
A 140-patient longitudinal study tracking severe aortic regurgitation over a median 93 months reveals that current surg…
PREPRINTStudies
TOF-MRA Matches CTA for Circle of Willis Hemodynamic Modeling
Researchers compared two imaging methods for mapping blood vessels in the brain's circle of Willis, finding that time-o…
Studies
California Flavored Tobacco Bans Cut Youth Vaping by 2.4 Percentage Points
Local tobacco policy interventions now demonstrate measurable effects on adolescent nicotine consumption patterns, offe…
Studies
Palmitoylation Emerges as Key Target for Pancreatic Cancer Immunotherapy
Pancreatic cancer's notorious resistance to immunotherapy may finally have an exploitable weakness. This devastating di…
Studies
Robotic Hysterectomy Benefits Over Laparoscopic Remain Unclear Despite Complex Case Advantages
The surgical treatment landscape for benign gynecologic conditions faces a compelling paradox: while robotic technology…
Studies
COVID Vaccine Waste Hit 21% Rate, Preventing 160M Additional Doses
The staggering scale of vaccine waste during America's COVID-19 response reveals systemic inefficiencies that could und…
Wellbeing
Maternal Stress Hormones Synchronize Fetal Circadian Clocks Before Birth
The timing of when human biological clocks first start ticking has profound implications for lifelong health patterns,…
Wellbeing
Fetal Circadian Clocks Synchronize with Maternal Rhythms via Glucocorticoid Signaling
The timing of when human biological clocks first tick has long puzzled researchers, with implications for understanding…
Studies
Gene Edit Enables CAR-T Cells to Program Lasting Anti-Tumor Immunity
The promise of CAR-T cell therapy for solid tumors may finally be within reach through a breakthrough that transforms t…
Fitness
Higher Step Counts Associated With Offsetting Sedentary Disease Risks for Some Conditions
The modern struggle between desk jobs and health just got quantified in unprecedented detail, revealing how many extra…
Studies
Keratin 16 Protein Suppresses Immune Inflammation in Skin Barrier Defense
The body's largest organ may have a previously unrecognized immune regulator working quietly beneath the surface. New m…
Longevity
Plasma Acetic Acid Links Gut Microbes to Brain Volume in Older Adults
Specific gut microbial communities produce acetic acid that circulates in plasma and directly influences multiple healt…
Longevity
Glial Cell Dysfunction Actively Drives Brain Aging: Insights from Single-Cell Analysis on Heterogeneity and Regional Vulnerability
Advanced single-cell analysis reveals that glial cells—microglia, astrocytes, and oligodendrocytes—undergo dramatic cel…
Longevity
CAR-T Cell Senolytic Therapy Fails to Improve Outcomes in ALS Mouse Model
NKG2D CAR-T cells successfully eliminated senescent astrocytes and reduced inflammatory secretions in the central nervo…
Longevity
Cellular Senescence Links Preeclampsia to Accelerated Cardiovascular Aging
Preeclampsia triggers cellular senescence—a state where cells stop dividing but release inflammatory molecules—creating…
Wellbeing
Seven Evidence-Based Strategies Could Cut Eating Disorder Treatment Dropout Rates
Treatment dropout represents one of the most significant barriers to eating disorder recovery, yet receives surprisingl…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.