Studies
Liver Cancer Lactate Hijacks Macrophage Fat Metabolism to Silence Immune Attacks
Understanding why immunotherapy often fails in hepatocellular carcinoma (HCC)—one of the most treatment-resistant…
Studies
Human Antibodies from WNV Survivors Neutralize Five Encephalitic Flaviviruses
With no approved treatment or prophylaxis for West Nile virus infection — a pathogen that kills thousands and leaves…
Wellbeing
Early Life Stress Rewires Brain Differently in Males Versus Females
Why anxiety and depression strike men and women so differently—and respond so differently to treatment—has long…
Studies
PSMA-PET Imaging Reframes PSA Persistence as Stage Marker, Not Prognosis Driver
For men who undergo radical prostatectomy, a detectable PSA level that never fully clears has long been treated as an…
Studies
Most U.S. Adults Unaware Alcohol Raises Cancer Risk, Survey Finds
Public health campaigns have long warned about drunk driving and liver disease, yet the alcohol-cancer connection…
Studies
Lumateperone Adjunct Significantly Improves Sexual Function in Treatment-Resistant Depression
Sexual dysfunction is one of the most underreported yet treatment-limiting side effects in antidepressant therapy…
Studies
Dimensionality Reduction Matches Expert Accuracy in Single-Sample Leukemia MRD Detection
Detecting vanishingly small populations of residual cancer cells after treatment is one of oncology's most…
Studies
Pulsed Field Ablation Doubles 12-Month Success Rate Over Drug Therapy in AFib
For the roughly 1 in 50 adults who develop persistent atrial fibrillation, current guidelines still relegate catheter…
Studies
Retinal Scans Predict Atrial Fibrillation Risk With 0.96 AUROC in High-Risk Patients
Atrial fibrillation's stealth is its danger — roughly a third of AF cases are diagnosed only after a stroke or other…
Longevity
Self-Efficacy Outweighs Physical Function in Predicting Successful Aging at 85+
What separates those who thrive in their late eighties from those who merely survive may have less to do with physical…
Nutrition
Gut Microbiome Composition Predicts and Shapes Immunotherapy Outcomes in Solid Tumors
For cancer patients receiving immunotherapy, why some respond dramatically while others barely at all has long been…
Studies
Macrophage Epigenetic Regulator SETDB1 Suppresses Liver Transplant Injury via Pyroptosis Pathway
Liver transplantation outcomes hinge on a poorly understood inflammatory cascade that erupts the moment blood flow is…
Nutrition
GLP-1 Drugs Shrink Fat and Muscle: What the Lean Mass Loss Actually Means
As semaglutide and tirzepatide reshape obesity medicine, a critical question has emerged that the weight-loss…
Studies
Global Myocarditis Burden Fell 60% in Mortality Yet Cases Surged 54%
Cardiovascular inflammation rarely commands the same public attention as coronary artery disease or heart failure, yet…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB and HIV Co-infection Trends 1990–2023
Tuberculosis remains one of the most consequential infectious diseases in human history, yet its trajectory over the…
Studies
ML Model Doubles Lp(a) Screening Yield in Cardiovascular Disease Patients
Lipoprotein(a) remains one of cardiovascular medicine's most underdiagnosed risk factors — genetically determined…
Nutrition
Western Diet Linked to Faster Attention Decline in APOE ε4 Carriers
For the estimated 25% of adults carrying at least one APOE ε4 allele — the strongest known genetic risk factor for…
Studies
Retinal Imaging Plus Biomarkers Achieve 0.85 AUC for Preeclampsia Delivery Prediction
Predicting when a pregnancy complicated by hypertension will require urgent delivery remains one of obstetric…
Longevity
IGFBP5 Reverses Stem Cell Senescence via WNT5B, Restoring Bone Regeneration
IGFBP5 expression drops significantly in dental follicle stem cells (DFSCs) undergoing both replicative and oxidative…
Supplements
GLP-1 Drugs Cut 3.4 kg Fat But Also Erode 0.78 kg Lean Mass
Across three randomized controlled trials enrolling 171 non-diabetic adults with obesity, GLP-1 receptor agonist…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.