PREPRINTStudies
Gabapentin-Calcium Channel Blocker Order Doubles Dementia Risk in 7,141 Patients
Adding gabapentin to existing calcium channel blocker therapy increased dementia risk by 144% (hazard ratio 2.44)…
PREPRINTLongevity
Vietnam CVD Deaths Rise 43% by 2050 Despite Mortality Rate Halving
Vietnam's cardiovascular disease landscape reveals a striking demographic paradox: while age-standardized mortality…
PREPRINTLongevity
Type 1 Diabetes Linked to Earlier Clonal Hematopoiesis Onset by ~7 Years in Large UK Biobank Study
Type 1 diabetes patients develop clonal hematopoiesis—abnormal blood cell clones—approximately 7 years earlier than…
PREPRINTStudies
GLP-1 Drugs Associated With ~28-33% Lower Stroke Risk vs SGLT2 Inhibitors in 195,072 Veterans (Preprint)
GLP-1 receptor agonists reduced stroke risk by 33% compared to SGLT2 inhibitors in a massive retrospective analysis of…
PREPRINTLongevity
Left Atrial Stiffness Changes Predict Heart Failure Risk in Hypertension
Analysis of 1,442 hypertensive patients revealed that worsening left atrial stiffness index over 6-18 months nearly…
Wellbeing
Moderate Coffee Intake Shows Neutral-to-Favorable Cardiovascular Outcomes Despite Acute Effects
The cardiovascular safety of caffeine consumption remains one of the most clinically relevant questions for…
Studies
Exosomes Show Dual Promise and Risk for Skin Cancer Treatment
Exosomes derived from mesenchymal and adipose-derived stem cells exhibit potent regenerative capabilities, enhancing…
Wellbeing
Bedtime Screen Use Disrupts Sleep More Than Daily Screen Time
The timing of digital device use emerges as more critical than total usage when examining sleep quality in young…
Studies
AI Framework Reduces Radiation Exposure 35% in Cervical Cancer Treatment
Radiation therapy for cervical cancer patients may soon become significantly safer and more precise through artificial…
Studies
Malaria Research Needs Dual Strategy: Optimize Current Tools, Prepare for Emerging Threats
The global fight against malaria stands at a critical juncture where progress has stagnated while new challenges…
Longevity
APOE2 Longevity Gene Activates DNA Repair Mechanisms in Human Neurons
The genetic lottery of exceptional longevity may hinge on cellular maintenance mechanisms that operate far beyond…
Studies
Breast Cancer Cases Projected to Rise Over 50% by 2050, Global Analysis Reveals
The trajectory of women's health faces an unprecedented challenge as demographic shifts and lifestyle changes converge…
Studies
Cruise Ship Hantavirus Outbreak Reveals Critical Gaps in Maritime Disease Preparedness
Maritime travel increasingly exposes passengers to exotic pathogens in settings where rapid response capabilities…
Wellbeing
Breast Imaging Guidelines Clarify Safety During Lactation for Cancer Screening
Lactating mothers facing breast cancer concerns no longer need to choose between timely diagnosis and continuing…
Wellbeing
Childhood Maltreatment Linked to Poorer Cognition in Bipolar Disorder, With Partial Mediation by Inflammation
The cognitive struggles that plague many adults with bipolar disorder may trace back to childhood experiences in ways…
Studies
Cruise Ship Hantavirus Outbreak Reveals Critical Gaps in Maritime Disease Preparedness
Maritime travel increasingly intersects with remote wilderness regions where rare zoonotic pathogens lurk, creating…
Supplements
Creatine 5g Daily Plus Resistance Training Builds Muscle in Postmenopausal Women
A meta-analysis of seven randomized trials involving 608 postmenopausal women found that creatine monohydrate…
Longevity
17α-Estradiol Extends Male Lifespan Without Major Feminizing Effects
17α-estradiol, a structural variant of conventional estrogen, demonstrates remarkable male-specific longevity benefits…
Fitness
Global Physical Activity Gap Shows 40-Point Disparity Between Rich and Poor
A striking inequality emerges when examining how different populations engage in voluntary physical activity…
Nutrition
Saudi Lactating Mothers Show Mixed Nutritional Knowledge Despite Strong Cultural Food Traditions
Traditional food wisdom may not translate to optimal maternal nutrition during one of the most metabolically demanding…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.