Longevity
Rapamycin Boosts Cerebral Blood Flow 15%+ in APOE4 Carriers at Low Dose
A pilot single-arm trial administered 1 mg/day rapamycin for 4 weeks to 23 cognitively normal adults aged 45–65…
Longevity
PD-L2 Checkpoint Lets Senescent Cells Evade Immunity, Driving Age-Related Decline
Senescent cells exploit the immune checkpoint protein PD-L2 to evade immune clearance, accumulating with age and…
Longevity
Cycloastragenol Extends C. elegans Lifespan 30% via Dual IIS/p38 MAPK Mechanism
At an optimal concentration of 0.2 μM, cycloastragenol (CAG) — a triterpenoid extracted from Astragalus membranaceus…
Longevity
Mitochondrial Haplotype Drives Accelerated Ovarian Aging via TOMM20-TFAM Import Failure
In genetically heterogeneous rat cohorts sharing equivalent nuclear backgrounds but differing in mitochondrial…
Studies
Very Hot Drinks Triple Squamous Oesophageal Cancer Risk in Million-Person UK Study
Most cancer-prevention messaging around beverages focuses on alcohol or sugar content — but the temperature at which…
Studies
Single-Cycle FDG-PET Predicts Chemotherapy Response in Triple-Negative Breast Cancer
For women with triple-negative breast cancer — one of the most aggressive and hardest-to-treat subtypes — knowing…
Nutrition
Over 225 Trials Support Intermittent Fasting for Type 2 Diabetes Management
For the tens of millions of adults managing type 2 diabetes or living with prediabetes, a significant gap exists…
Studies
Heart Regeneration Review: iPSC Cardiomyocytes Show Promise but Arrhythmia Risk Persists
Heart failure remains one of medicine's most stubborn unsolved problems — not because we can't open blocked arteries…
Longevity
Centenarian Immune Systems Reveal Molecular Blueprints for Exceptional Healthspan
What if the immune system held the master key to living past 100 in good health? A comprehensive review in Nature…
Longevity
Cognitive Resilience Cuts Alzheimer's Risk Even With High Amyloid Burden
The long-standing assumption that amyloid and tau accumulation alone determine who develops Alzheimer's dementia is…
Studies
Bispecific Antibody Teclistamab Outperforms Standard Therapy in Pre-Symptomatic Myeloma
Intercepting multiple myeloma before it fully develops has long been a tantalizing but elusive goal. For the roughly…
Studies
International Consortium Positions Medical Digital Twins as Precision Health Infrastructure
The convergence of computational modeling, real-time biosensing, and artificial intelligence has quietly been building…
Longevity
Astrocyte Protein Links APOE4 Gene Variant to Alzheimer's Vascular Breakdown
Understanding why carriers of the APOE ε4 allele face dramatically elevated Alzheimer's risk has remained one of the…
Studies
Beta-3 Adrenoceptor Activation Stabilizes Plaques by Blocking Perivascular Fat Ferroptosis
Plaque rupture, not plaque formation, is what actually kills — and that distinction has long frustrated cardiovascular…
Studies
Liver Protein HRG Identified as Key Brake on Heparin-Induced Clotting Disorder
Heparin remains one of medicine's most widely used anticoagulants, yet a paradoxical and potentially fatal…
Studies
SGLT2 Inhibitors and GLP-1 Agonists Redefine Treatment Across Heart-Kidney-Metabolic Disease
The therapeutic goalposts for type 2 diabetes have shifted decisively. What began as glucose management has evolved…
Studies
Mental Disorder Prevalence in Poorest Nations Set to Hit 18,000 per 100,000 by 2050
The mental health crisis in the world's poorest nations is accelerating faster than most health systems can absorb…
Studies
AI-Enhanced ECG Detects 21% More Coronary Occlusions Than Standard Care
One in four heart attack patients is currently being missed at emergency triage — not because of physician error, but…
Studies
Multi-Component ACP Interventions Boost Dementia Care Planning Readiness
For families navigating a dementia diagnosis, the window for meaningful end-of-life planning closes gradually but…
Nutrition
Plant-Predominant Diets With Tailored Protein Intakes Extend Healthspan Across Life Stages
A whole-food, plant-predominant diet (WFPD) delivers broad cardiometabolic and mental health benefits through multiple…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.