Studies
Network Meta-Analysis Ranks Best Drug Options for Antipsychotic Weight Gain
Antipsychotic-induced weight gain sits at the intersection of two major health crises: the undertreatment of serious…
Studies
AI Agent MIRA Surpasses Physicians in EHR-Integrated Diagnostic Accuracy
The boundary between clinical decision support and autonomous clinical action has just been meaningfully crossed. For…
Studies
AI Agent MIRA Surpasses Physicians in Diagnostic Accuracy Within EHR Systems
The assumption that artificial intelligence in medicine would remain a background assistant — surfacing information…
Studies
AI Reads Single-Lead ECG to Detect Four Heart Failure Subtypes Simultaneously
Silent cardiac dysfunction — particularly the notoriously difficult-to-diagnose heart failure with preserved ejection…
Studies
Advanced Immunotherapies Severely Compromise Vaccine Efficacy in Rheumatic Disease Patients
For the millions of adults living with autoimmune rheumatic diseases, the calculus around vaccination is far more…
Studies
Novel Lipid Nanoparticle Variant Boosts mRNA Vaccine Safety and Potency
The delivery mechanism of mRNA vaccines has quietly been one of the most consequential—and least discussed—variables…
PREPRINTLongevity
Belly Fat Drives Lacunar Stroke 30% Via Blood Pressure, MR Study Finds
Using two-sample Mendelian randomization mediation analysis across 16 candidate biomarkers, abdominal…
PREPRINTLongevity
Copper Cell-Death Genes Show No Causal Link to Heart Disease Risk
Despite striking transcriptional activation of cuproptosis and copper-transport genes in atherosclerotic plaque…
PREPRINTLongevity
Metabolically Dysfunctional Lean Individuals Face Same CAD Risk as Obese, Via Different Pathways
A two-sample Mendelian randomization study using 60,801 coronary artery disease cases from CARDIoGRAMplusC4D found…
PREPRINTLongevity
Only 0.9% Tested: Lp(a) Above 125 nmol/L Drives 67% Higher PCI Risk
Across 687,780 primary prevention patients in the PITT-LIPID real-world registry, only 6,340 (0.9%) ever received…
PREPRINTFitness
Seated Heel-Raises Every 10 Minutes Cut Stroke Patients' Blood Pressure Rise by 42%
Among 15 chronic stroke patients (mean age 69.3 years), three hours of uninterrupted sitting elevated central systolic…
Wellbeing
Higher Self-Efficacy Drives Non-Pharmacological Pain Relief Choices in Labor
The relationship between a woman's psychological confidence and her labor experience has long been underappreciated in…
Fitness
Concussions Lead Injury Profile in World's First Body-Checking Women's Hockey League
When a sports governing body rewrites the rules of contact for female athletes, the injury consequences deserve…
Studies
48-Hour Cooling After Cardiac Arrest Shows No Brain Recovery Advantage Over 24 Hours
For the millions of people who survive an out-of-hospital cardiac arrest only to face devastating neurological injury…
Studies
Intrawound Tobramycin Fails to Reduce Tibial Fracture Infection Rates in Trial
The assumption that flooding a surgical wound with antibiotics guarantees lower infection rates has long guided…
Studies
Blood Transfusion as Overlooked Peanut Allergen Delivery Route Identified
For the millions of individuals living with peanut allergy, risk management has long focused on oral ingestion…
Studies
Adding Chemotherapy to Osimertinib Extends Progression-Free Survival in Dual-Mutant Lung Cancer
For the roughly one-third of EGFR-mutated lung cancer patients who also carry TP53 mutations — a genomic co-occurrence…
Studies
Phase 3 Trial: Adding Chemotherapy to Osimertinib Improves EGFR-Mutant Lung Cancer Outcomes
For patients carrying both EGFR and TP53 mutations in advanced non-small cell lung cancer, treatment resistance has…
Studies
EGFR-Mutated Lung Cancer: Combination Therapy Gains Come With Serious Toxicity Trade-offs
For patients living with the most common genomic subtype of advanced lung cancer, a fundamental treatment question is…
Studies
VA System Active Surveillance Adoption Gaps Revealed in Prostate Cancer Cohort
For men diagnosed with low-risk prostate cancer, watchful waiting rather than immediate treatment has become the…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.