Studies
Cancer Pain Mechanisms Mapped: Immune Cells, Glia, and Sex Hormones Reshape Treatment
Chronic pain affects a substantial proportion of cancer patients at every stage of disease, yet it remains…
Studies
Primary Aldosteronism Linked to 56% Pregnancy Complication Rate in European Cohort
For the estimated one in ten hypertensive adults whose elevated blood pressure stems from excess aldosterone…
Studies
B7-H3 ADC Shows Modest 7% Response Rate With High Toxicity Burden
For patients exhausting treatment options in advanced solid tumors, antibody-drug conjugates represent one of…
Studies
COPD Stability at 6 Months Cuts Mortality Risk by Half in Phase 3 Data
For the roughly 300 million people living with chronic obstructive pulmonary disease worldwide, treatment goals have…
Studies
Global Burden Data: Secondhand Smoke Drives 266,000 Annual COPD Deaths
For the millions of adults who have never smoked, COPD has long seemed like someone else's disease. This large-scale…
Studies
128-Study Review Maps Weight Stigma's Deep Roots Across Latin America
Obesity care fails when bias precedes treatment. Across Latin America and the Caribbean, a pervasive but underexamined…
Studies
SHP2-ERK Dual Blockade in KRAS-Mutant Cancers Halted by Multi-Organ Toxicity
KRAS-mutant pancreatic cancer remains one of oncology's most formidable challenges, with fewer than 12% of patients…
Studies
Acoramidis Slows Kidney Decline by 71% in Cardiac Amyloidosis Trial
Cardiac amyloidosis patients already face a compounding burden: the same misfolded transthyretin protein that…
PREPRINTNutrition
RCT-plus-MR Framework Links 10 Proteins to Lifelong Diabetes Risk from Diet
A novel two-step analytical framework combining short-term dietary RCT data with Mendelian randomisation (MR) can…
PREPRINTLongevity
Typhoons Kill 2,426 Elderly Japanese in Decade: Healthcare Access Drives Risk
A Bayesian spatio-temporal analysis linking 12.9 million Japanese deaths (2010–2019) to population-weighted typhoon…
PREPRINTStudies
10,000-Patient VOYAGER Consortium Maps HPV and Genomics in Oral Cancer
The VOYAGER consortium has assembled one of the largest head and neck cancer (HNC) genomic resources to date, pooling…
PREPRINTLongevity
Mid-life Weight Loss From Obesity Restores Cardiometabolic Trajectory to Healthy-Weight Rates by Age 62
Among 6,309 participants from the 1958 British birth cohort tracked from ages 44 to 62, adults who gained weight into…
PREPRINTLongevity
Triple-Domain Risk Score Predicts 6x Higher AFib Risk in Hypertensive Adults
Among 7,261 hypertensive adults in the SPRINT trial followed for a median 3.76 years, 174 developed atrial…
Fitness
Female Runners With Knee Injuries Show Distinct Hip Motion Patterns Versus Males
Rehabilitation protocols for running-related knee injuries have long been applied relatively uniformly across sexes…
Studies
Pre-Diagnosis Frailty Independently Predicts 37% Higher Mortality in CLL Patients
For the nearly one million Americans living with chronic lymphocytic leukemia or small lymphocytic lymphoma, standard…
Longevity
Senolytics and Senomorphics Show Dual Promise Against Atherosclerotic Plaque Inflammation
Even when LDL cholesterol is well-controlled, older adults with cardiovascular disease often keep experiencing plaque…
Studies
SGLT2 Inhibitors Cut ACOS Risk by 30–38% in Largest Network Meta-Analysis
For the estimated 15–25% of obstructive airway disease patients who carry a dual asthma-COPD diagnosis, treatment…
Studies
Endocannabinoid System Shows Promise for Alcohol Use Disorder — Human Evidence Lags
Alcohol use disorder affects hundreds of millions worldwide, yet the pharmacological toolkit remains narrow and…
Wellbeing
New 18-Question Scale Quantifies Hidden Anxiety Burden in Thyroid Cancer Patients
Anxiety in thyroid cancer is systematically overlooked by the clinicians who treat it — and that gap has real…
Studies
MIXPRS Framework Boosts Polygenic Risk Accuracy Across Non-European Populations
Polygenic risk scores hold enormous promise for identifying individuals at elevated risk of complex diseases before…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.