PREPRINTFitness
Correcting Accelerometer Errors Reveals 56% Stronger CVD Protection From Daily Movement
Applying a novel statistical pipeline — combining accelerated failure time models, spline regression, and…
Studies
Major 2026 Guidelines Unify Obesity, Kidney Disease, and Heart Risk Management
For decades, cardiology, nephrology, and endocrinology operated in largely separate clinical silos — treating heart…
Studies
CDK2 Inhibition Boosts Immunotherapy Efficacy via BRD4-Mediated Transcriptional Reprogramming
The discovery that a well-known cell-cycle kinase doubles as a transcriptional gatekeeper — and that blocking it could…
Studies
Workplace First Responders Score High on CPR Knowledge But Gaps Persist Across Departments
Sudden cardiac arrest kills within minutes, and the first person on scene — not a paramedic — is usually the one who…
Nutrition
NLP Analysis Reveals Income-Driven Gaps in Global Dairy Dietary Guidance
How a country frames its dietary advice may reveal as much about its economic standing as its nutritional science. A…
Studies
PARP1 Enzyme Drives Neuropathic Pain via Glial Redox Reprogramming
Chronic neuropathic pain remains one of the most therapeutically resistant conditions in medicine, partly because its…
Longevity
Hippo-IGF2 Axis Controls Liver Size and Rescues Age-Impaired Regeneration
A newly characterized Hippo-IGF2 signaling axis governs both developmental organ sizing and regenerative capacity. In…
Fitness
Resistance Training Preserves Tongue Motor Function in Low-Aerobic-Capacity Aging Rats
In 18–24-month-old rats selectively bred for high (HCR) or low (LCR) aerobic capacity, resistance exercise training…
Longevity
Midlife GH Receptor Knockout Extends Lifespan and Feminizes Male Liver Transcriptome
Ablating the growth hormone receptor (Ghr) in 12-month-old mice — equivalent to roughly midlife — extended lifespan in…
Studies
Epigenetic Reprogramming of Motor Neurons Amplifies Stroke Rehabilitation Outcomes in Mice
One of the most stubborn barriers to stroke recovery is not the injury itself, but the aging brain's diminished…
Studies
Clopidogrel Alone Matches Dual Antiplatelet Therapy After Stent Implantation
For the millions of adults living with coronary artery disease and a drug-eluting stent, the question of how long to…
PREPRINTStudies
Temple Wearable Tracks Brain Blood Flow With r=0.80 vs Gold-Standard Doppler
A temple-worn optical wearable device, outputting a proprietary dimensionless Brain Flow index, correlated strongly…
PREPRINTStudies
Bayesian Reanalysis of 60,619 Patients Challenges Prasugrel's Superiority After Heart Attack
A Bayesian network meta-analysis of 19 randomized controlled trials encompassing 60,619 patients undergoing PCI after…
PREPRINTLongevity
AI Reconstructs 3D Heart Geometry From ECG Alone in 71,000 Patients
A conditional flow-matching model called visionECG, trained on 71,132 paired ECG and cardiac mesh sequences from the…
PREPRINTLongevity
Novel MVX Biomarker Links Metabolic Inflammation to 12% Higher Mortality Risk in 218,635 Adults
In a prospective analysis of 218,635 UK Biobank participants followed for a median 14.4 years, each standard deviation…
PREPRINTLongevity
Urine Peptide Clock Predicts Death Risk with 48% Higher Hazard Per SD
A urinary peptidomic biological age clock built from capillary electrophoresis-mass spectrometry data across 17,000+…
Supplements
Oral GLP-1 Drugs Achieve >10% Weight Loss Without Injections
Two oral incretin-based therapies — oral semaglutide (a peptide GLP-1 receptor agonist) and orforglipron (a…
Studies
AI Agent Forecasts Maternal and Infant Risk From Longitudinal Health Records
When pregnancy complications go undetected until a crisis point, outcomes for both mother and newborn worsen…
Wellbeing
Smartphones at 13 Linked to Depression, Obesity, and Sleep Loss at 14
The debate over when adolescents should receive their first smartphone has largely been driven by advocacy and…
Studies
Mental Health Now Second Most Common Pediatric Hospitalization Diagnosis in 2022
A quiet but consequential shift has occurred inside America's children's hospitals: mental health crises have…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.