Wellbeing
Hormone Therapy Shows Neutral Effect on Dementia Risk Across Studies
Meta-analysis of existing studies found menopausal hormone therapy (MHT) neither increases nor decreases dementia risk…
Wellbeing
Modifiable Risk Factors Could Prevent Half of Dementia Cases in Norway
Analysis of 14 established dementia risk factors in Norwegian population data reveals that comprehensive lifestyle…
Studies
Physician Training Plus Patient Education Halves Unnecessary Antibiotic Prescriptions
A cluster randomized trial across rural Chinese clinics demonstrated that combining physician training with real-time…
Studies
Diabetes Patients Prioritize Quality of Life Over Glucose Control in Islet Therapy
Patient-reported priorities for stem cell-derived islet transplantation diverge significantly from traditional…
Studies
Bispecific T-Cell Engagers Show Promise for Treatment-Refractory Autoimmune Connective Tissue Diseases in Case Series
Ten patients with severe, treatment-resistant autoimmune conditions—five with antisynthetase syndrome and five with…
Longevity
Soluble IL-6 Receptor Shows Protective Effects Against All-Cause Mortality
Mendelian randomization analysis reveals that while interleukin-6 (IL-6) increases mortality risk, its soluble…
Studies
Plasma p-tau217 Clock Accurately Forecasts Alzheimer's Symptom Timeline
Researchers developed predictive algorithms using plasma p-tau217 levels to forecast when cognitively healthy…
Longevity
Multiple Functional Deficits Predict Mortality Better Than Individual Measures
Analysis of 12,906 Chinese adults revealed that accumulating multiple age-related functional impairments creates a…
Studies
Swedish Trial: Colonoscopy and FIT Boost Early-Stage Colorectal Cancer Detection
A population-based screening trial involving over 270,000 Swedish adults demonstrated that both colonoscopy and fecal…
Studies
Tau-Targeting BIIB080 Shows Exploratory Trends Toward Slowing Alzheimer's Cognitive Decline in Phase 1b Trial
BIIB080, an antisense oligonucleotide designed to reduce tau protein production, demonstrated meaningful cognitive…
Longevity
Blood Stem Cell Mutations Enhance Cancer Immunotherapy Effectiveness
Age-related mutations in blood stem cells, termed clonal hematopoiesis of indeterminate potential (CHIP), appear to…
Studies
Plasma AT(N) Biomarkers Show Promising Accuracy (AUC 83-88%) Distinguishing Alzheimer's from Frontotemporal Dementia in Latin Americans
Plasma AT(N) biomarkers—measuring amyloid, tau, and neurodegeneration markers—demonstrated high diagnostic accuracy in…
Longevity
Breast Tissue Senescence After Weaning Enables Repair But Raises Cancer Risk
Mammary gland involution following weaning triggers widespread cellular senescence that orchestrates tissue remodeling…
Longevity
Midlife Visceral Fat Expansion Isn't Universally Harmful, Nature Review Reveals
White adipose tissue accumulation around abdominal organs during midlife follows predictable patterns, but its…
Wellbeing
Loneliness Linked to 31% Higher Dementia Risk in Multi-Cohort Analysis
Analysis of multiple National Institute on Aging population cohorts reveals that subjective loneliness correlates with…
Wellbeing
Financial Missteps Precede Dementia Diagnosis by Several Years
Payment delinquencies on mortgages and credit cards emerge as measurable indicators of cognitive decline occurring…
Wellbeing
White Matter Hyperintensities Emerge as Modifiable Alzheimer's Risk Markers
White matter hyperintensities—bright lesions visible on brain MRI scans originating from small vessel…
Longevity
New Mouse Model Maps Inflammation Pathways Driving Multi-Organ Aging Decline
NIA researchers created a novel mouse model that captures the cascade of inflammatory processes underlying…
Longevity
Dasatinib-Quercetin Senolytic Therapy Shows Subtle Bone Marker Changes but No Overall Bone Density Improvements in Postmenopausal Women
A placebo-controlled trial testing dasatinib plus quercetin in postmenopausal women with low bone density revealed…
Longevity
In Female Mice, Maternal X Chromosome Bias Accelerates Brain Cell Aging and Memory Decline
X-chromosome inactivation patterns inherited from mothers appear to selectively disable critical neuronal genes…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.