Supplements
Vitamin D3 and Omega-3 Fail to Reduce Dementia Biomarkers Over 4 Years
Four years of daily supplementation with vitamin D3 (2000 IU) and marine omega-3 fatty acids (1 g) produced no…
Longevity
Senescent Bone Cells' SASP Drives Osteoporosis via RANKL/Wnt/NF-κB Convergence
Senescent osteocytes, mesenchymal stem cells, osteoblasts, immune cells, and vascular endothelial cells collectively…
Studies
Skin's Moisture Sensor Identified: TRPV4 Channel Detects Atmospheric Dryness
Understanding how skin detects and responds to dry air has profound implications for conditions ranging from eczema…
Studies
Genomic Surveillance Maps Chikungunya Spread Via Human Density on Réunion
As climate change expands the habitat of Aedes mosquitoes into subtropical and temperate zones, understanding how…
Studies
Sensory Neuron TRPM2 Channels Identified as Direct Chronic Arthritis Pain Transducers
Chronic pain management remains one of medicine's most stubborn challenges, with arthritis patients often cycling…
Studies
New Evolutionary Framework Explains How Host-Specific Microbiomes Become Heritable
Understanding why each animal species carries a distinct, heritable microbial community — and how that specificity is…
Studies
NMR Crystallography Maps Enzyme Protonation States Behind Antibiotic Resistance
Antibiotic resistance is one of the defining medical crises of this century, and a precise understanding of how…
Studies
Actin Filament Network ACTA2 Identified as STING Transport Gatekeeper
Understanding how the immune system fires its first molecular alarm against viral invaders has profound implications…
Studies
Beta-Catenin–TRIM28 Complex Controls Hormone-Driven Gene Transcription in Kidney Cells
Understanding how mature, fully differentiated cells regulate gene expression in response to hormones has direct…
Studies
Taste Receptor Structural Flexibility Explains Why Both Sugar Forms Taste Sweet
Understanding why the human tongue can detect such a broad chemical landscape using just a handful of receptors has…
Studies
3D Chromatin Restructuring Drives Lasting Innate Immune Memory After Inflammation
Understanding how immune cells remember past threats could reshape strategies for managing chronic inflammation…
Studies
Alternative Splicing of Syt7 Protein Acts as Master Switch for Synaptic Plasticity
Understanding how the brain fine-tunes communication between neurons has profound implications for neurological…
Longevity
Lysosomal Protein TM6SF1 Links Cholesterol Sensing to mTORC1 Nutrient Signaling
Understanding how cells detect nutrient availability and adjust growth accordingly sits at the heart of aging biology…
Studies
Gut-Resident Immune Cells Reprogram to Favor Localized Antiviral Interferon Over Systemic Response
The intestinal immune system faces a paradox that researchers have long struggled to resolve: how does the gut mount…
Studies
AMPylation Enzyme SelO Suppresses Tumors via Cdk5rap3 Protein Modification
Most cancer research focuses on familiar signaling pathways—phosphorylation cascades, ubiquitin-mediated degradation…
Studies
Local Interferon Delivery Unlocks Immune Visibility in Pediatric Brain Tumors
Childhood brain cancer treatment has long been stalled by a brutal paradox: the therapies aggressive enough to shrink…
Wellbeing
Gun Proximity Measurably Weakens Cognitive Control in Two Preregistered Experiments
Mental performance is rarely discussed in the context of firearm exposure, yet the environment surrounding a person…
Studies
NEJM Editorial Frames Liquid Biopsy Progress Toward Cancer's Early-Detection Goal
Early cancer detection has long been the most promising — and most elusive — frontier in oncology. The difference…
Studies
NEJM Trial: Multicancer Blood Test Cuts Late-Stage Diagnoses Across Tumor Types
Early cancer detection has long been the holy grail of oncology, yet most screening tools target single tumor types…
Studies
Ceperognastat Trial Finds No Cognitive Benefit in Early Alzheimer Patients
One of the least-explored molecular pathways in Alzheimer's disease — the O-GlcNAc modification system — has now been…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.