Supplements
Resveratrol Shields Fish Gut via PPAR/NF-κB During Heat Stress
Heat stress in Siberian sturgeon triggers UCP1-mediated uncoupling of ATP synthesis from oxidative phosphorylation…
Studies
Triclosan Drives 48.5% of Liver Stress via Gut Bacteria Desulfovibrio in Children
Among school-aged children co-exposed to bisphenol S, triclosan (TCS), and methylparaben, elevated AST/ALT ratios — a…
Longevity
15 Epigenetic Clocks Predict Longevity But Miss Cognitive Healthspan in 5,844 Women
Among 5,844 postmenopausal women tracked from the mid-1990s, every standard deviation increase in epigenetic age…
Studies
HCV-Specific CD4+ T-Cells Harbor Replication-Competent HIV Reservoirs During Coinfection
One of the most stubborn obstacles to an HIV cure is understanding exactly which cells hide replication-competent…
Studies
AI Pain Detection in Children Shows Multimodal Fusion Outperforms Single-Signal Models
Accurately measuring pain in children—especially in infants and neonates who cannot self-report—remains one of…
Studies
Rimegepant Delivers Consistent Migraine Relief Across Repeated Real-World Attacks
For the roughly one billion people worldwide living with migraine, finding an acute treatment that works reliably…
Studies
CRISPR Cuts Huntingtin Protein Up to 80% in Mouse Models, Raising Gene Therapy Hope
Huntington's disease has long represented one of genetic medicine's most frustrating frontiers: a single…
Studies
Clinical AI Fails Deployment Tests Despite Strong Lab Performance
A persistent and costly gap exists between how well AI performs in controlled research settings and how it actually…
Studies
RSV Vaccines Cut Hospitalization 70% in Immunocompromised Adults, IDSA Confirms
For the millions of adults living with compromised immune systems — whether from cancer treatment, organ…
Studies
BioPROTACs Emerge as Biological Alternative to Small-Molecule Protein Degraders
The ability to selectively eliminate disease-driving proteins — rather than merely inhibit them — represents one of…
Studies
Methylation at IRF3 Lysine-98 Reveals New Brake on Innate Antiviral Immunity
Understanding how the immune system knows when to stop fighting a virus is as important as understanding how it starts…
Studies
Structural Blueprint of Leukemia-Linked DNMT3A Mutant's Aberrant Protein Assembly Revealed
Understanding how a single amino acid substitution can derail the epigenetic machinery governing blood cell…
Studies
Enzyme Switch on Immune Cells Sprouts Cancer-Promoting Sugar Structures
The immune cells supposed to protect us can be co-opted by tumors — and now researchers have pinpointed a specific…
Studies
Gut Bacteria Coordinate Serotonin Output Through Specialized Intestinal Sensor Cells
Understanding how the gut microbiome actually talks to the nervous system — in real mechanistic detail — has been one…
Studies
Calbindin Protein Divides Dopamine Neurons Controlling Speed, Learning, Exploration
Understanding exactly which dopamine neurons die in Parkinson's disease — and what each population actually does — has…
Studies
Legionella Hijacks Host Histone Marks to Redirect Its Own Epigenetic Attack
Understanding how bacteria manipulate human gene expression at the chromatin level could reshape how infectious…
Nutrition
Low-Carb Diets Reshape Gut Microbiome Via Fat-Protein Macronutrient Pathways
For the millions of adults experimenting with low-carbohydrate eating patterns, a critical question has remained…
Studies
GDF-15 Links Tumor Stiffness to Vascular Chaos and Immune Evasion in Melanoma
A single protein appears to sit at the intersection of three of melanoma's most dangerous properties — its ability to…
Studies
Chloride Ion Co-Transport With Serotonin Reshapes SERT Mechanism Understanding
For the tens of millions of people taking SSRIs or other serotonin-targeting antidepressants, the molecular machinery…
Studies
Farm Soil Management Directly Controls Antibiotic Resistance Gene Spread
Antibiotic resistance is one of medicine's most pressing threats, and most attention has focused on hospitals and…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.