Wellbeing
Estrogen Decline Maps to Six Cognitive Domains in Menopausal Women
For roughly half the global population, the menopausal transition represents an underappreciated neurological…
Nutrition
Polyphenol Mix Raises LDL Numbers Yet Cuts Oxidized LDL in Postmenopausal Women
Standard lipid panels may be telling an incomplete story for postmenopausal women taking polyphenol supplements. When…
Longevity
Midlife GDF15 Protein Predicts Dementia Risk 25 Years Later via Neuroimmune Pathways
Most dementia risk scores focus on lifestyle factors and genetics measured close to diagnosis — but a growing body of…
Studies
CDT Thrombolysis Trial Redefines Clot Treatment for High-Intermediate PE Risk
Pulmonary embolism sits at a dangerous crossroads where undertreatment risks death and overtreatment risks…
Studies
Tirzepatide and CagriSema Lead 19-Drug Obesity Meta-Analysis Covering 99,000 Patients
The landscape of obesity pharmacotherapy has shifted so rapidly in the last five years that clinicians and patients…
Studies
Phase 3 Trial: Atezolizumab Fails EFS in Early TNBC, But Tumor Subtype Signal Emerges
Triple-negative breast cancer remains one of oncology's most difficult targets precisely because it lacks the…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB and HIV Co-infection Trends 1990–2023
Tuberculosis remains one of the most consequential infectious disease challenges of our era, and at a moment when…
Nutrition
Fluconazole Reshapes IBD Gut Fungal Balance Where Nystatin Falls Short
For the millions living with inflammatory bowel disease, the gut microbiome's bacterial inhabitants have long…
Longevity
NRF2 Pathway in Oligodendrocytes Linked to Variable Cognitive Aging Rates
Most interventions targeting age-related cognitive decline have focused on neurons, amyloid plaques, or tau tangles…
Studies
Blood Protein ISM2 Flags Preeclampsia Risk in First Trimester
Identifying dangerous pregnancy complications before symptoms emerge has long been one of obstetric medicine's most…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB Progress Lags Dangerously
With global health funding under unprecedented pressure and WHO's 2035 End TB targets still a distant aspiration for…
Studies
Benzylpenicillin Matches Anti-Staphylococcal Penicillins in PSSA Bloodstream Infection
For decades, clinicians have defaulted to broader anti-staphylococcal penicillins even when bloodstream infections are…
PREPRINTLongevity
Post-TAVI Butyrate Decline Correlated with IL-18 Elevation via Gut-Immune Axis in Small Preprint Study
In 40 patients undergoing transcatheter aortic valve implantation (TAVI), circulating short-chain fatty acid (SCFA)…
PREPRINTStudies
730-Case SEER Registry Reveals Two Distinct Cardiac Tumor Types With Divergent Survival Profiles
Among 730 primary malignant cardiac tumor (PMCT) cases from the SEER-18 registry (2000–2021), two biologically…
PREPRINTLongevity
GPT-4o Detects RV Overload and PH Co-occurrence at Higher Rates Than Rule-Based Systems in 45k Echo Reports
Applying GPT-4o within a secure clinical enclave to 45,794 echocardiography reports from MIMIC-III, LLM-based…
Studies
NOAC Monotherapy Cuts Valve Thrombosis After TAVI Without Extra Bleeding Risk
For the millions of adults living with aortic valve stenosis, the choice of blood-thinning therapy after a…
Longevity
CD38 Overexpression Strongly Associated with NAD⁺ Depletion in Menopause, Accelerating Aging
Chronic inflammation and CD38 overexpression emerge as the dominant molecular drivers of progressive intracellular…
Studies
Low-Dose 2-Hour Catheter Thrombolysis Cuts RV Strain in Pulmonary Embolism
For patients facing life-threatening pulmonary embolism with right heart strain, the clinical calculus has long been…
Studies
Large Cohort Study Finds GLP-1 Drugs Carry Similar Neuropsychiatric Risk Profiles
As GLP-1 receptor agonists become some of the most widely prescribed medications in the world, a critical question for…
Studies
Sham-Controlled Trial Challenges AF Ablation's Quality-of-Life Benefit
For decades, catheter ablation has been a cornerstone treatment for symptomatic atrial fibrillation, endorsed by major…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.