Longevity
CD38 Overexpression Strongly Associated with NAD⁺ Depletion in Menopause, Accelerating Aging
Chronic inflammation and CD38 overexpression emerge as the dominant molecular drivers of progressive intracellular…
Studies
Low-Dose 2-Hour Catheter Thrombolysis Cuts RV Strain in Pulmonary Embolism
For patients facing life-threatening pulmonary embolism with right heart strain, the clinical calculus has long been…
Studies
Large Cohort Study Finds GLP-1 Drugs Carry Similar Neuropsychiatric Risk Profiles
As GLP-1 receptor agonists become some of the most widely prescribed medications in the world, a critical question for…
Studies
Sham-Controlled Trial Challenges AF Ablation's Quality-of-Life Benefit
For decades, catheter ablation has been a cornerstone treatment for symptomatic atrial fibrillation, endorsed by major…
Longevity
51-Study Meta-Analysis Identifies Which Epigenetic Clocks Best Track Longevity Interventions
The ability to measure whether an anti-aging intervention is actually working — without waiting decades for mortality…
Studies
Systematic Review Protocol Targets Diet-Exercise Combos for Overweight AF Patients
Atrial fibrillation affects millions of adults worldwide, and its rising prevalence tracks closely with the global…
Studies
Nurse-Digital Hybrid Care Cuts Heart Failure Mortality in Large Indian RCT
Heart failure management in low- and middle-income countries has long lagged behind high-income settings, not from…
Studies
mHealth Cardiac Rehab Shows Greater VO2 Peak Improvement vs Center-Based in Heart Failure Meta-Analysis
For the millions of heart failure patients who cannot reliably access clinic-based rehabilitation — due to geography…
Studies
Cryo-EM Reveals Two Distinct Activation Pathways for Heart Failure Receptor RXFP1
Understanding precisely how a drug activates its target receptor — not just whether it binds — is emerging as one of…
Fitness
Ten Minutes of Slow Running Sharpens Prefrontal Function and Lifts Mood
The common assumption that exercise must be vigorous to deliver cognitive and emotional benefits is directly…
Wellbeing
Epilepsy Caregivers Score Two Standard Deviations Below Mental Health Norms
The psychological toll of caring for a child with a chronic neurological condition is frequently underestimated in…
Studies
IPV Associated with Measurable Share of HIV Burden in Women as Funding Cuts Threaten 2030 Goals
The intersection of gender-based violence and infectious disease burden rarely receives quantified, country-level…
Studies
FFR-Guided PCI Cuts Adverse Events Nearly in Half During TAVI Procedures
For the roughly one-third of patients undergoing transcatheter aortic valve replacement who also carry significant…
Studies
PREMIUM Trial Tests Aspirin-Free Prasugrel Strategy Immediately After Heart Attack Stenting
For patients suffering a heart attack requiring emergency stenting, the standard practice of combining aspirin with a…
Wellbeing
Female Brain Shows Stronger Sleep Spindle Activity in Meta-Analysis of 43 Studies
Sleep quality is rarely gender-neutral, yet the neurological basis of that disparity has remained stubbornly opaque. A…
Longevity
Middle-Aged Offspring of Alzheimer's Patients Show Early Cognitive Deficits with Elevated APOE4 Prevalence
For the estimated one in five adults carrying at least one APOE ε4 allele, the question of when Alzheimer's disease…
Studies
Hemodialysis Linked to Higher Mortality After TEER; Hemodynamic Success Markers Less Predictive
For cardiologists and patients navigating mitral valve disease alongside kidney failure, a fundamental assumption is…
Studies
Dendritic Cells Found to Orchestrate Anti-Tumor Immune Structures in Lung Cancer
For cancer immunotherapy to work better, the tumor microenvironment must sustain organized immune activity — not just…
Studies
Insulin Resistance Marker Linked to Benign Prostatic Hyperplasia in Two Large Cohorts
Prostate health and metabolic function have long been suspected to intersect, but the specific pathway connecting…
Studies
Takotsubo Syndrome Diagnosis Remains Challenging Despite Advances in Imaging and Emerging AI Tools
Heart disease that appears identical to a heart attack but resolves on its own represents one of cardiology's most…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.