Studies
Oral OGA Inhibitor Ceperognastat Tested in Early Alzheimer's RCT
Tau pathology sits at the heart of Alzheimer's neurodegeneration, and the search for drugs that can interrupt its…
Studies
Tau-Targeting Drug Ceperognastat Enters Alzheimer Clinical Testing Phase
With amyloid-clearing therapies now approved for early Alzheimer's, the field's next frontier is tau — the protein…
Studies
ACG 2025 Ulcerative Colitis Guidelines Reframe Adult Treatment Priorities
Inflammatory bowel disease affects roughly 1 million Americans with ulcerative colitis alone, and shifting treatment…
Studies
BCMA CAR-T Enterocolitis Linked to Mucosal Cytotoxic T Cell Expansion, Not Just B Cell Loss
As CAR-T cell therapies move from experimental to standard-of-care for blood cancers, their gastrointestinal side…
Studies
Deep Learning Screening Tool Validated Across Three Countries, One Million Patients
Most clinical AI tools are born and die in the hospital that created them — validated on local data, never tested…
Studies
Phase 3 Trial Validates ADC Therapy for Relapsed Small-Cell Lung Cancer
Small-cell lung cancer has long been one of oncology's most daunting diagnoses — not merely because it spreads…
PREPRINTNutrition
Poor Campus Food Access Raises Odds of Disrupted Meal Timing 9.5-Fold
Among 302 undergraduates (mean age 20 years, 68.9% female) at a Nigerian medical university, poor physical food…
PREPRINTNutrition
Feijoa Powder Cuts HbA1c by 0.5% in Prediabetic Adults Over 12 Weeks
A 12-week randomized controlled trial in 39 overweight adults with prediabetes (HbA1c 5.7–6.4%, BMI 25–29.9 kg/m²)…
PREPRINTStudies
Digitized Paper ECGs Yield 80% AI Correlation With Native Digital Files
A preliminary head-to-head comparison tested whether paper-derived ECGs, digitized via ECGScan software, could…
PREPRINTLongevity
GLP-1 Drugs Cut Mortality 60% in Heart Failure + Diabetes Patients
Among 77,758 propensity-matched patients with type 2 diabetes and heart failure with reduced ejection fraction…
PREPRINTLongevity
8 Novel Genes Linked to Silent Aortic Dissection Risk Across 890,000 Participants
Analyzing ultrarare damaging missense and predicted loss-of-function variants across five major biobanks—totaling more…
Nutrition
0.5%/0.5% Lysine-Arginine Ratio Cuts Tumor Burden; Wrong Ratio Accelerates Growth
A specific dietary amino acid ratio — 0.5% lysine combined with 0.5% arginine — reduces tumor burden and extends…
Studies
Tapeworm Drug Niclosamide Disrupts Breast Cancer Survival Pathway, Boosts Chemo Sensitivity
Repurposing existing drugs for cancer treatment has emerged as one of oncology's most pragmatic frontiers — bypassing…
Studies
Astrocytes Emerge as Key Architects of Glioma Progression and Resistance
Brain cancer research has long focused on tumor cells themselves, but a growing body of evidence implicates the…
Studies
Integrated Early Intervention Boosts Growth in Undernourished Term Infants
Small-for-gestational-age infants born at term face a compounding disadvantage: they enter the world already behind on…
Studies
Integrated Four-Domain Intervention Boosts Weight Gain in Underweight Newborns
Catch-up growth in infants born small-for-gestational-age remains one of the most consequential challenges in early…
Studies
Bundled Nutrition and Stimulation Interventions Show Mixed Results for At-Risk Infants
For the roughly 250 million children in low- and middle-income countries who fail to reach key developmental…
Studies
Large RCT Finds No Mortality Difference Between Two Major Anesthesia Types
For the millions of adults over 50 who undergo major elective surgery each year, the choice of anesthetic technique…
Studies
TIVA vs Inhaled Anesthesia: 30-Day Recovery Outcomes in Older Surgical Patients
For older adults facing major surgery, the choice of anesthesia method has long been assumed to be largely…
Studies
Phase III Trial: SBRT Matches MH-IMRT in Prostate Cancer Quality of Life
For the roughly 100,000 men diagnosed annually with intermediate-risk prostate cancer in the U.S., treatment choice…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.