PREPRINTNutrition
Personalized Meal Timing Cuts 2.1 kg in 6 Weeks—No Diet Required
Adults randomized to personalized meal schedules—derived from two weeks of app-based dietary records—lost 2.10 kg more…
PREPRINTLongevity
Hidden CAC Data in Breast Cancer PET Scans Could Reclassify Statin Need in 64% of Small Prevention-Eligible Subgroup
Coronary artery calcium (CAC) scores extracted from routine staging 18F-FDG PET/CT scans in 276 women with newly…
Longevity
GLP-1 Drugs Cut Obesity-Linked Cancer Risk 7–30% — But Causality Unproven
Large observational cohorts consistently link GLP-1 receptor agonist (GLP-1RA) exposure — drugs like semaglutide and…
Longevity
Sarcopenia Diagnosis Hinges on Grip Strength, Not Mass Alone
Sarcopenia—progressive loss of muscle strength, mass, and physical performance—is increasingly prevalent in aging…
Longevity
Exercise Modality and Timing Post-Menopause May Influence Alzheimer's Risk via BDNF and Brain Structure Pathways
Women comprise nearly two-thirds of Alzheimer's diagnoses, and the menopausal transition emerges as a discrete…
Studies
Newly Mapped Spinal Circuit Links Mechanical Pain Signals to Brain Stem
Chronic mechanical pain — the kind triggered by pressure, pinching, or tissue injury — remains one of the hardest…
Studies
Neutrophil Protein Vgll4 Blocks Tumor-Driven Immune Suppression via STAT Pathway
Understanding why the immune system fails to eliminate tumors is one of cancer biology's central puzzles — and a new…
Studies
Mitochondrial Calcium Signaling Shields Tumors From Ferroptotic Immune Destruction
Understanding why some cancers resist their own programmed destruction has long been central to improving…
Studies
Potassium Channel Gene Doubles Survival in Parkinson's Mouse Model
One of the most stubborn obstacles in Parkinson's disease research has been finding a way to interrupt α-synuclein…
Studies
JNK Inhibitors Show Promise Against Endometriosis Pain in Preclinical Models
Endometriosis affects roughly one in ten women of reproductive age globally, yet treatment options remain stubbornly…
Studies
USP14-FBXW7 Protein Rivalry Drives Drug Resistance in Head-Neck Cancer
Drug resistance remains the dominant reason curative intent fails in head and neck squamous cell carcinoma (HNSCC)…
Studies
Stem Cell Triculture Model Reveals Microglia Drive Retinal Neuron Loss
The mechanisms by which the brain's immune cells destroy retinal neurons have been nearly impossible to study in…
Studies
Conserved KAT2–PGK–ALDO Cascade Amplifies Glycolysis Under Cellular Energy Stress
When cells run low on energy, their survival depends on rapidly upshifting glucose metabolism — and how they…
Wellbeing
Nasal Breathing Frequency Causally Controls Anxiety via Dedicated Brain Circuit
Breathing exercises have long been prescribed for anxiety, yet the precise neural machinery converting nostril airflow…
Longevity
Hsp70 Chaperone Partners Show Stress-Selective Binding That Shapes Cellular Protein Quality Control
Protein quality control is one of the most consequential yet underappreciated pillars of healthy aging. When cells…
Nutrition
Domestication Erased Key Flavor Genes From Modern Tomatoes, PNAS Study Reveals
For anyone who has noticed that supermarket tomatoes taste oddly flat compared to heirloom or garden-grown varieties…
Studies
Rapid Cell Proliferation May Paradoxically Suppress Cancer Through Competition
Cancer prevention is rarely framed as a competition problem, yet emerging theoretical biology suggests that how…
Studies
Tumor Bacteria Enhance MR1 Expression and MAIT Cell Activation in Lung Cancer
The immune system's ability to recognize and destroy cancer cells depends heavily on the molecular signals that summon…
Studies
Nanopore Metagenomic Pipeline Identifies Bloodstream Pathogens in Hours, Not Days
Bloodstream infections are among the most time-sensitive emergencies in medicine — every hour without appropriate…
Studies
Viral Entry Triggers Nuclear DNA Expulsion, Activating Key Innate Immune Pathway
Understanding how cells first sense viral invasion has long been a central puzzle in immunology — and the answer has…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.