PREPRINTStudies
Brazilian ACS Registry: Women's Chest Pain 51% More Likely Deemed 'Possibly' Ischemic
Among 7,171 acute coronary syndrome (ACS) patients across 14 Brazilian states (2020–2024), women faced systematically…
PREPRINTLongevity
DBP at 80–90 mmHg Peaks Bone Density; ACE Inhibitor Target MMP9 Cuts BMD by 3.6%
In 366,443 UK Biobank participants of European ancestry, diastolic blood pressure (DBP) showed a striking inverted…
PREPRINTLongevity
Mavacamten Linked to 81% Lower Adverse Events vs. Septal Ablation in 220-Patient oHCM Registry Study
In a propensity-matched single-center registry of 220 adults with obstructive hypertrophic cardiomyopathy (oHCM)…
Studies
Autonomous Robotic Blood Draw Achieves 94.5% First-Stick Success Across Difficult Populations
Blood draws are among the most performed clinical procedures globally, yet they remain surprisingly error-prone…
Studies
Bariatric Surgery Cuts CKD Risk but RYGB Raises Hyperoxaluria Danger
Obesity-related glomerulopathy — driven by glomerulomegaly, focal segmental glomerulosclerosis, and hyperfiltration…
Studies
Dopamine-Grafted Cellulose Hydrogel Preserves Retinal Ganglion Cells After Optic Nerve Crush
Vision loss from optic nerve injury remains one of medicine's most stubborn challenges — the retinal ganglion cells…
Studies
Mitochondrial Carrier SLC25A13 Shields Triple-Negative Breast Cancer from Immune Attack
Triple-negative breast cancer is notoriously unresponsive to immunotherapy, and understanding why tumors evade immune…
Studies
RadImageNet Transfer Learning Classifies Adult Scoliosis Severity from X-rays
Spinal curvature assessment remains one of the most measurement-dependent judgments in musculoskeletal radiology — two…
Studies
PROTAC AR Degrader Plus Abiraterone Shows Tolerability Signal in Resistant Prostate Cancer
For men whose metastatic prostate cancer has stopped responding to standard androgen-pathway blockade, treatment…
Supplements
Single Patient Experiences Decade-Long Remission Following Selenite Then Chemotherapy: Case Report
Complete, durable remission in a patient with no remaining standard treatment options is among the rarest and most…
Studies
Ten-Protein Serum Signature May Predict Relapse Risk in Rare CNS Autoimmune Disease
For a disease where each relapse can permanently erode neurological function, predicting who is about to deteriorate…
Studies
Chemoimmunotherapy Combination Doubles Pathologic Response Rates in Head and Neck Cancer
For patients facing locally advanced head and neck squamous cell carcinoma, the window before surgery may be more…
Supplements
Ketone Esters Preserve Muscle Mass Lost During Semaglutide Weight Treatment
One of the most underappreciated trade-offs of GLP-1 receptor agonist therapy is that a substantial portion of the…
Studies
SGK1 Kinase Suppresses Microglial Cleanup, Accelerating ALS Progression in Mice
For a disease with no meaningful disease-modifying therapy, ALS research desperately needs mechanistic footholds…
Wellbeing
Newborn Hippocampal Neurons Suppress Overactive Circuits to Lift Depression
For millions living with treatment-resistant depression, electroconvulsive therapy (ECT) remains one of the most…
Studies
Daily Zinc Cuts Infection Rate by One-Third in Young Sickle Cell Patients
For children with sickle cell anemia in sub-Saharan Africa, infections are not a complication — they are a leading…
Studies
Misconceptions, Fear, and Competing Priorities Are Key Barriers to Lung Cancer Screening, Scoping Review Finds
Lung cancer remains the leading cause of cancer mortality worldwide, yet low-dose CT screening — a tool proven to…
Studies
China-Developed Drugs Surge in Global Approvals: A 35-Year Regulatory Analysis
The global pharmaceutical landscape is shifting in ways that matter profoundly for patients, payers, and health…
Studies
CCT/TRiC Chaperonin Links Therapy-Induced Senescence to Glioblastoma Progression via SASP and Stem-Cell Pathways
Glioblastoma multiforme cells subjected to standard radiotherapy and temozolomide frequently enter therapy-induced…
Longevity
Sheaf Theory Math Model Reframes 12 Aging Hallmarks as Repair Obstruction Cascade
A mathematical framework using sheaf theory and algebraic topology proposes that the twelve hallmarks of aging are not…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.