Novel PKA Inhibitor Reveals Unexpected Enzyme Conformation With Therapeutic Potential
Protein kinase A dysfunction underlies numerous age-related diseases, from diabetes to neurodegeneration, making precis…
Protein kinase A dysfunction underlies numerous age-related diseases, from diabetes to neurodegeneration, making precis…
Understanding how the delicate machinery of hearing self-organizes could unlock new approaches to treating hearing loss…
Understanding how cells synthesize DNA building blocks could unlock new approaches to cancer treatment and aging resear…
The emergence of novel influenza strains capable of human infection represents one of the most significant ongoing thre…
Cellular senescence operates as a dynamic spectrum of states rather than the traditional binary on/off switch previousl…
Preventing babies from being born too small or too early remains one of global health's most persistent challenges, wit…
A critical gap exists in preventing the autoimmune destruction that defines type 1 diabetes, where the body's T cells s…
Sleep disruption during menopause affects millions of women, yet standard insomnia treatments often fail to address the…
Sleep disruption affects up to 85% of children with cerebral palsy, creating cascading health problems and family stres…
Housing arrangements fundamentally shape how older adults view and adopt health-supporting technologies in their homes.…
Analysis of 6.8 million Lombardy residents revealed that one in four adults remained undervaccinated by mid-2022, with…
Researchers developed a three-stage computational pipeline using Mendelian randomization to systematically identify exi…
Potassium-containing low-sodium salt substitutes consistently reduced systolic blood pressure by 4.6-8.9 mmHg and diast…
Daily supplementation with NatureU Mind Care BeautyU Caps for 56 days was associated with a 47% reduction in crow's-fee…
Researchers developed a brief, image-based rating tool that measures two key dimensions of food evaluation—liking and p…
Researchers analyzing UK Biobank cardiac imaging data identified papillary muscle hypertrophy as a promising new biomar…
Plasma neurofilament light chain (NfL), a biomarker of neuronal axonal injury, independently predicted major cardiovasc…
Machine learning analysis of four cardiac surgery cohorts revealed that patients with multiple long-term conditions seg…
Analysis of 1,185 cognitively normal older adults revealed distinct sex-specific patterns of cognitive decline based on…
Scientists developed an optical biopsy system that measures aging in retinal cells—specifically ganglion, bipolar, and…
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