Fitness
12-Week RT+HIIT Shows Minimal Transcriptomic Gains; Polyphenols Add Nothing
A 12-week supervised concurrent resistance training plus HIIT programme in 38 adults aged 55–70 years produced…
Fitness
Training at Peak vs. Trough Time of Day Makes No Difference for Older Adults
A 12-week randomized controlled trial in 93 adults (mean age 67) found that matching resistance training to an…
Supplements
Higher Omega-3 Blood Levels Linked to Less Amyloid in APOE4 Carriers
Among 104 cognitively normal older adults enriched for preclinical Alzheimer's disease (69.2% preclinical AD, 44.2%…
Wellbeing
Healthy Sleep Cuts Stroke Risk 14% Via Lipid and Inflammation Pathways
In 200,729 UK Biobank participants followed for a median 12.6 years, each one-point improvement on a six-component…
Nutrition
Dietetic Counseling Cuts Systolic BP 5–7 mmHg; Wearables Add Modest Pulse Pressure Benefit
In a 954-person, three-arm RCT of adults aged ≥55 with metabolic syndrome risk factors, all intervention groups…
Studies
Weekly Dual GIP/Glucagon Agonist Cuts Weight Significantly in Obese Diabetics
The convergence of obesity and type 2 diabetes represents one of the most consequential metabolic challenges in modern…
Studies
Semaglutide Shows Measurable Kidney-Protective Mechanisms in Diabetic Patients
Chronic kidney disease is the leading cause of end-stage renal failure in adults with type 2 diabetes, and slowing its…
PREPRINTWellbeing
Repeated Partner-Inflicted Head Injuries Age Women's Brains by Up to 28 Years
Among 207 women with lifetime exposure to physical intimate partner violence, those reporting ten or more…
PREPRINTLongevity
Frequent High-NO2 Days Accelerate 14-Year Cognitive Decline in Older Adults
Among 12,235 English adults aged 50 and older followed for up to 14 years in the English Longitudinal Study of Ageing…
PREPRINTLongevity
HDL Cholesterol Shows J- and U-Shaped Mortality Curves in 150,000 Adults
In 47,123 Mexican men and 97,589 women followed prospectively, HDL cholesterol showed non-linear associations with…
PREPRINTWellbeing
Sleep Hypoxic Burden Outperforms AHI for Heart Failure Prognosis Over 3.7 Years
Among 178 heart failure patients not receiving airway pressure therapy — followed for a median 3.7 years after acute…
PREPRINTLongevity
Meeting BP, LDL, and A1c Targets Still Leaves 2–4× CV Risk Gap by Social Context
Among adults in the All of Us cohort who already met standard cardiovascular prevention targets — systolic BP below…
Nutrition
Heart-Healthy Diet Cuts Fatty Liver Odds by 84% in Iranian Adults
In a case-control study of 675 Iranian adults (225 NAFLD cases, 450 controls), those scoring in the highest tertile of…
Nutrition
Personalized Dietary Plans Beat Usual Care for MASLD Weight Loss by 6.7 kg
Across 14 randomized controlled trials enrolling 1,805 adults with metabolic dysfunction-associated steatotic liver…
Studies
Lean MASLD Carries Similar Long-Term Mortality Risk as Obese MASLD
In a multinational retrospective study of 18,326 biopsy-confirmed MASLD patients across 41 countries, lean individuals…
Wellbeing
Smoking After Heart Attack Doubles Mortality Risk vs. Quitters
Among 65,990 Spanish adults tracked across three national health surveys (2011–2017) and linked to mortality data…
Studies
Triple Hormone Agonist Retatrutide Drives Substantial Weight Loss in Phase III Trial
Obesity pharmacotherapy is entering a new era, and the latest data suggest the ceiling on drug-induced weight loss may…
PREPRINTWellbeing
Insomnia at 50 Predicts Cognitive Decline; Same Symptom Reverses After 75
Across 16,884 adults from three longitudinal cohorts (ELSA, Whitehall II, and Rush MAP), difficulty falling asleep at…
PREPRINTStudies
CGM-Detected Glucose Spikes Raise Liver Scarring Risk 28–59% in Non-Diabetics
In 1,071 adults from the Framingham Heart Study Third Generation cohort (mean age 60.2, BMI 28.2, 56% normoglycemic)…
PREPRINTWellbeing
Six Lifestyle Clusters Predict Dementia Risk: Worst Combo Raises Hazard 2.4×
Among 151,832 UK Biobank participants aged 60–69, six distinct clusters of co-occurring modifiable risk factors were…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.