PREPRINTStudies
3% Annual SCD Risk Threshold Optimizes ICD Therapy Benefits
Meta-analysis of 18 randomized controlled trials reveals that patients with a 3% annual sudden cardiac death (SCD) risk…
Studies
MAO-B Inhibition Shows Promise for Diabetic Nerve Damage Treatment
Diabetic peripheral neuropathy affects over half of diabetes patients, causing debilitating pain and numbness that curr…
Studies
Tuberculosis Treatment Fails to Restore Normal Life Expectancy
Even successful tuberculosis treatment may not fully restore health prospects, challenging assumptions about infectious…
Studies
Blood Test Detects Burkitt's Lymphoma in African Children
Early cancer detection in resource-limited settings could transform survival outcomes for children facing one of the fa…
Studies
AI Mammography Screening Falls Short of Radiologist Double-Reading Standard
The promise of artificial intelligence revolutionizing breast cancer screening faces a significant reality check, as au…
Wellbeing
Regional Energy Transition Disparities Linked to Unequal Air Pollution Deaths
The promise of Europe's green energy transition faces a harsh reality check: regions lagging in renewable adoption are…
Studies
GLP-1 Drugs Associated with 15% Lower Risk of Major Cardiovascular Events in Type 1 Diabetes: Study
The cardiovascular benefits of GLP-1 receptor agonists may extend far beyond their established role in type 2 diabetes…
Studies
Blood Tau Protein Test Detects Multiple Amyloid Diseases Beyond Alzheimer's
The discovery that a single blood test could identify multiple protein misfolding diseases represents a potential break…
Studies
Genetic Analysis Finds No Causal Link Between GLP-1 Drugs and Mental Health Disorders
The meteoric rise of GLP-1 receptor agonists like semaglutide and tirzepatide for weight management has sparked concern…
Studies
Feline Cancer Genetics Mirror Human Oncogenes in 493 Tumor Analysis
The striking genetic parallels between feline and human cancers could accelerate therapeutic development for both speci…
Wellbeing
Dopamine Circuit Model Links Cortical Inhibition Deficits to Schizophrenia Symptoms
Excessive cortical excitation may fundamentally disrupt how the brain learns to navigate complex environments, offering…
Studies
3D X-Ray Imaging Reveals Hidden Architecture of Cirrhotic Liver Disease
The inability to see liver disease progression in three dimensions has long handicapped efforts to understand why cirrh…
Studies
Chinese Birth Cohort Tracks Environmental Exposures in 100,000 Pregnancies
Understanding how environmental chemicals shape fetal development could revolutionize prenatal care and public health p…
Studies
Serotype 3 Pneumococcus Drives Severe Childhood Infections Despite Vaccination
The COVID-19 pandemic's disruption of pathogen circulation patterns has created unexpected vulnerabilities in childhood…
Studies
Liver Deaths Nearly Double Over 25 Years, Alcohol Leading Driver
The trajectory of liver disease mortality in America reveals a troubling reversal of public health gains achieved in ot…
Wellbeing
Review Using Collaborative Cross Mice Highlights Links Between Autoimmune Conditions and Dementia Risk
The traditional view of dementia as purely a brain disorder is being fundamentally challenged, with implications for ho…
Studies
GLP-1 Drugs Show Antidepressant Effects Beyond Weight Loss Control
Popular weight loss medications like semaglutide and liraglutide may be quietly reshaping mental health treatment along…
Studies
Clozapine and Combination Therapy Show Superior Cannabis-Induced Psychosis Prevention
Cannabis-induced psychosis affects thousands annually, with relapse rates approaching 50% despite treatment. Finding th…
Studies
ABCA7 Gene Variant Linked to Reduced Brain Network Adaptability in African Americans
Brain network flexibility—the capacity to dynamically reconfigure neural connections—may serve as an early warning syst…
Studies
ApoB and Lipoprotein-A Emerge as Superior Cardiovascular Risk Predictors
The insurance industry's need for precise cardiovascular risk assessment at a single point in time has spotlighted crit…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.