Found 2029 results for "cancer"
Most longevity research focuses on the centenarians themselves, but the more actionable question may be what happens to their children. If the biology that…
The question of whether the plastic particles now saturating our food, water, and air are quietly reshaping cancer risk has moved from fringe concern to…
One of the most stubborn frustrations in modern oncology is that CAR-T cell therapy — transformative for blood cancers — largely stalls at the gates of solid…
Cancer survivorship carries a burden that extends well beyond the tumor itself — and for the millions living through and beyond treatment, psychological and…
Pancreatic cancer kills with such ferocity partly because it is virtually invisible until advanced stages — and because no reliable early biomarker exists. A…
Among the most pharmacologically important proteins in human biology, G-protein-coupled receptors govern everything from pain perception and immune cell…
Heterozygous loss of Brca1 — mirroring germline BRCA1 mutations in humans — produces a striking paradox: female mice on a high-fat diet develop exacerbated…
Doxorubicin chemotherapy in young (3-month) and aged (20-month) male and female mice triggered accelerated skeletal aging — trabecular bone loss, increased…
The assumption that regulatory clearance guarantees superior clinical performance is one of medicine's quietly held beliefs — and a new benchmarking study…
Two decades of American health data reveal a striking paradox: medicine has become remarkably effective at extending life from the diseases it has…
Understanding why colorectal cancer so frequently spreads to the liver—and why some metastatic cells outcompete healthy tissue so efficiently—is one of…
The assumption that every person accumulates DNA errors at roughly the same pace has quietly underpinned cancer risk models and genetic disease counseling for…
Fibrosis — the runaway scarring that stiffens and destroys organs — kills more people globally than many cancers, yet therapeutic options remain limited…
For the millions of cancer survivors left with chronic nerve pain after chemotherapy, the lack of both predictive biomarkers and effective treatments has been…
For millions of adults who survived childhood cancer, the treatments that saved their lives may have left lasting biological fingerprints — including changes…
Lung nodules occupy a peculiar and anxiety-inducing space in modern medicine: discovered incidentally on millions of chest scans each year, the vast majority…
One of medicine's most entrenched rituals — the annual checkup — has surprisingly thin evidentiary footing, and a perspective published in the New England…
For decades, RAS mutations were considered undruggable — a death sentence for targeted therapy in lung cancer. The emergence of agents capable of broadly…
For decades, drug development operated on a single dominant logic: find a target protein, block its activity. The approval of the first PROTAC compound for…
Cellular senescence — the state in which damaged cells halt division but resist death and emit inflammatory signals — has long been implicated in aging…