MOGAT2 Enzyme Inhibitor VB-85387 Triggers Metabolic Shift Reducing Obesity
The struggle to maintain weight loss after GLP-1 therapy highlights a critical gap in obesity treatment—the need for interventions that create lasting metaboli…
Found 40 results for "fasting"
The struggle to maintain weight loss after GLP-1 therapy highlights a critical gap in obesity treatment—the need for interventions that create lasting metaboli…
Multiple exercise modalities—endurance, high-intensity intervals, and resistance training—alongside ketogenic diets and intermittent fasting all elevate brain-…
The widespread supplementation with branched-chain amino acids (BCAAs) may require reconsideration given emerging evidence that these popular workout nutrients…
GLP-1 receptor agonists demonstrate striking efficacy in prediabetes reversal, with tirzepatide achieving normoglycemia in 93.3% of patients, semaglutide in 81…
A six-month randomized controlled trial examined whether 1.15 grams daily of whole fruit feijoa powder could enhance metabolic benefits of weight loss in 97 ov…
Understanding why diabetes medications work brilliantly for some patients while failing others could transform personalized treatment approaches. A specific ge…
Skeletal muscle-specific deletion of FoxO1, FoxO3, and FoxO4 transcription factors in mice dramatically worsened fatty liver disease during prolonged fasting,…
Skeletal muscle may hold unexpected keys to preventing fatty liver disease during periods of caloric restriction or intermittent fasting. This finding challeng…
Analysis of 8,653 participants followed from birth to age 49, plus 13,795 UK Biobank participants aged 40-79, reveals that metabolic health stratification emer…
Longevity interventions demonstrate markedly different efficacy between males and females, with response variations potentially linked to baseline lifespan dif…
The discovery of metabolic master switches often emerges from unexpected cellular machinery. A previously overlooked RNA-binding protein called HuR has now bee…
Eight months of caloric restriction and resveratrol supplementation failed to prevent functional brain connectivity loss or cognitive decline in TgF344-AD rats…
A machine learning model successfully predicted which individuals would maintain weight loss 12 weeks after a 5-day fast, using baseline gut microbiome composi…
Mendelian randomization analysis using genome-wide genetic variants as instrumental variables demonstrates that pescatarian dietary patterns causally reduce fa…
Environmental toxin exposure may be silently undermining metabolic health in ways that interact dangerously with genetic predisposition and lifestyle choices.…
Each hour delay in starting daily food intake was associated with 0.88 mU/l higher fasting insulin, 16.17 mU/l higher post-meal insulin, and 0.30 units higher…
A subtle metabolic marker measured just one hour after glucose intake may identify the optimal window for diabetes prevention efforts. This finding challenges…
The conventional understanding of human motivation may need fundamental revision. Rather than chasing pleasure or subjective rewards, our brains appear primari…
The transition through menopause brings metabolic shifts that can destabilize weight regulation for decades, yet the hormonal mechanisms governing these change…
Astrocytes—the brain's primary support cells—undergo extensive metabolic and structural changes when exposed to ketone therapies including ketogenic diets, int…