Gut Cells Sense Food Quantity Via Cytoplasmic Fluidity to Control Cell Fate
How intestinal cells decide whether to renew, differentiate, or die has long been framed around molecular signals — hormones, growth factors, specific…
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How intestinal cells decide whether to renew, differentiate, or die has long been framed around molecular signals — hormones, growth factors, specific…
Maintaining genomic integrity during cell division is one of the most demanding tasks biology faces — and failures here are directly linked to cancer…
Tuberculosis remains one of the most consequential infectious diseases in human history, yet its burden is unevenly distributed and deeply entangled with HIV…
Most people assume the body simply wears out — accumulating molecular errors until systems fail. A compelling theoretical review challenges that intuition…
Among 1,226 patients enrolled in a virtual cardio-kidney-metabolic program, dermatologic side effects of GLP-1 receptor agonist therapy scaled sharply with…
Chronic mTOR hyperactivation drives ovarian aging through suppressed autophagy, mitochondrial dysfunction, impaired proteostasis, and oxidative stress in…
For older adults, maintaining independence and avoiding hospitalization are defining health priorities — yet a highly preventable respiratory threat remains…
For women who experience menopause before age 45, the biological clock is already working against them — but new evidence suggests that social and economic…
Understanding how the body's inflammatory machinery assembles at the molecular level could eventually reshape how clinicians target chronic inflammatory…
More than a million people still die from gut infections every year — and most of those deaths are preventable. This latest GBD 2023 analysis offers the most…
For anyone tracking biological age through DNA methylation tests, this research delivers an important reality check. The assumption that a technically precise…
Iron-driven cell death may be quietly undermining heart and vascular health across a far wider spectrum of conditions than previously appreciated — and…
For the roughly 50 million people living with dementia worldwide — and the larger population at risk — the pace of progress in tau biology may be the single…
The idea that a core metabolic cofactor—one derived from dietary riboflavin and present in virtually every human cell—could simultaneously regulate two of the…
Three decades of progress against tuberculosis are real but dangerously incomplete — and recent collapses in global health funding now threaten to unravel…
For decades, Alzheimer's disease was diagnosed primarily through cognitive decline — meaning intervention came only after substantial neurodegeneration had…
For decades, cardiovascular exercise dominated longevity conversations, but mounting evidence is repositioning resistance training as an equally critical…
Gut health in older adults may be more tightly tied to systemic inflammation than previously understood — and a newly identified molecular circuit explains…
Tuberculosis remains one of humanity's most consequential infectious disease failures — a curable disease that still kills more people annually than almost…
In esophageal squamous cell carcinoma (ESCC) patient cohorts, high intratumoral expression of fibrillarin (FBL), a nucleolar rRNA methyltransferase…