Found 68 results for "fasting"
The growing body of evidence supporting dietary restriction's role in extending healthspan creates compelling opportunities for targeted interventions that don…
Depleting Integrator complex subunits in adult C. elegans extends both lifespan and healthspan by disrupting RNA 3' end processing. Loss of the catalytic subun…
Researchers identified 5-androstene-3β,17β-diol (ADIOL), a steroid hormone discovered nearly 100 years ago, as the molecular bridge connecting fasting and calo…
University of Pittsburgh researchers conclude that while humans can survive months without calories and intermittent fasting may activate beneficial metabolic…
The growing popularity of GLP-1 medications for weight management has created an unexpected procedural safety concern that could affect millions of users under…
Cellular recycling mechanisms may be more critical to muscle health than previously understood, particularly for individuals carrying genetic variants affectin…
Type 1 diabetes treatment could be revolutionized by solving one of transplant medicine's most persistent challenges: keeping newly transplanted insulin-produc…
Fatty liver disease affects millions worldwide, yet how liver cells manage sudden influxes of dietary fats has remained a metabolic mystery. Understanding this…
The struggle to maintain weight loss after GLP-1 therapy highlights a critical gap in obesity treatment—the need for interventions that create lasting metaboli…
Multiple exercise modalities—endurance, high-intensity intervals, and resistance training—alongside ketogenic diets and intermittent fasting all elevate brain-…
The widespread supplementation with branched-chain amino acids (BCAAs) may require reconsideration given emerging evidence that these popular workout nutrients…
GLP-1 receptor agonists demonstrate striking efficacy in prediabetes reversal, with tirzepatide achieving normoglycemia in 93.3% of patients, semaglutide in 81…
A six-month randomized controlled trial examined whether 1.15 grams daily of whole fruit feijoa powder could enhance metabolic benefits of weight loss in 97 ov…
Understanding why diabetes medications work brilliantly for some patients while failing others could transform personalized treatment approaches. A specific ge…
Skeletal muscle-specific deletion of FoxO1, FoxO3, and FoxO4 transcription factors in mice dramatically worsened fatty liver disease during prolonged fasting,…
Skeletal muscle may hold unexpected keys to preventing fatty liver disease during periods of caloric restriction or intermittent fasting. This finding challeng…
Analysis of 8,653 participants followed from birth to age 49, plus 13,795 UK Biobank participants aged 40-79, reveals that metabolic health stratification emer…
Longevity interventions demonstrate markedly different efficacy between males and females, with response variations potentially linked to baseline lifespan dif…
The discovery of metabolic master switches often emerges from unexpected cellular machinery. A previously overlooked RNA-binding protein called HuR has now bee…
Eight months of caloric restriction and resveratrol supplementation failed to prevent functional brain connectivity loss or cognitive decline in TgF344-AD rats…