Orexin Neurons Encode Reward Prediction Signals Driving Motivated Effort
Understanding what neurologically separates persistent effort from giving up has profound implications for treating addiction, depression, apathy, and…
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Understanding what neurologically separates persistent effort from giving up has profound implications for treating addiction, depression, apathy, and…
Psychological trauma following severe physical injury is a clinically underappreciated comorbidity — yet orthopedic surgeons rarely consider psychiatric…
Accelerometry data from 2,809 adults in the Northern Finland Birth Cohort 1966 (46-year follow-up) reveals stark occupational divides in how physical…
Whether genetic makeup determines who is most harmed by chronic short sleep—at least in terms of Alzheimer's-related brain changes—is a question with profound…
Treating adolescent ADHD without the cardiovascular risks and abuse potential of traditional stimulants has been a long-standing clinical challenge. A new…
Memory consolidation during sleep has long been assumed to flow through a single hub — the hippocampus — before radiating outward to cortical and subcortical…
In a pilot randomized crossover study of 20 adults in New York City, the compact cuff-integrated SOMNOmedics ABPM Pro device produced markedly better…
Precision medicine for aging has long promised individualized interventions but rarely delivered them in a rigorous, multi-modal format. The PROMETHEUS trial…
Mental health research has long been dominated by urban, high-income populations — making findings from 1,107 rural Ghanaian farmers both scientifically…
Sleep is often framed as the brain's recovery period, but that framing may be far too simple. New imaging work in living mice challenges a foundational…
Tracking sleep health trends in young people depends critically on whether the measurement tools used remain consistent across time — a methodological concern…
Eczema is rarely framed as a mental health emergency — but for children and adolescents living with atopic dermatitis, the psychological toll may be far more…
Sleep deprivation is rarely framed as an organizational management problem — yet the conditions employers set around psychological safety may shape whether…
Understanding exactly how the sleeping brain converts daytime motor practice into lasting skill has been a central puzzle in neuroscience—and the answer has…
Continuous, real-world cardiac data collected outside clinic walls may be one of the most underutilized assets in modern cardiovascular care — and the gap…
Brain waste clearance is emerging as one of the most consequential mechanisms in Alzheimer's disease prevention, and a non-invasive MRI technique may now…
Migraine affects roughly one billion people globally, yet its underlying biology remains poorly understood — a gap that shapes why treatments frequently fall…
Motor skill retention overnight has long been attributed to sleep quality, but precisely which neural events are doing the memory work — and what disrupts…
Sleep-disordered breathing during pregnancy has long occupied a clinical blind spot — undertreated partly because guidance on how to act on it simply didn't…
Aggregated nocturnal cough data from the Sleep Cycle smartphone app—covering January 2023 to January 2026 across England—demonstrated strikingly strong…