DREAM Complex Knockout Extends Mouse Lifespan by Reducing DNA Damage
A fundamental mechanism controlling cellular aging may have been unlocked through understanding how cells balance DNA repair against energy conservation. This…
Found 1715 results for "cancer"
A fundamental mechanism controlling cellular aging may have been unlocked through understanding how cells balance DNA repair against energy conservation. This…
Resveratrol-loaded liposomes significantly protected ovarian function in mice exposed to cyclophosphamide chemotherapy by activating the HIGD1A/NF-κB/SOD2…
Extracellular vesicles from embryonic stem cells successfully reversed chemotherapy-induced ovarian failure in mice, restoring estrous cycles, fertility, and…
The widespread use of herbs and spices containing methyleugenol—from basil to nutmeg—may pose greater liver risks than previously understood, as new cellular…
Neuroendocrine tumors present a unique treatment challenge, often diagnosed at advanced stages when complete surgical removal appears impossible. This…
Healthcare equity advocates have long suspected that racial disparities extend far beyond access to care, affecting treatment quality and outcomes even within…
The global healthcare system faces an unprecedented challenge as cancer cases surge worldwide while the workforce needed to diagnose and treat them fails to…
Clear cell renal cancer, one of the most treatment-resistant malignancies, may soon face a more precise diagnostic weapon. The challenge has been…
Cancer immunotherapy's unpredictable efficacy may finally have an explanation rooted in an overlooked immune organ. While current biomarkers focus on tumor…
Cancer survivors face a harsh trade-off: life-saving chemotherapy treatments that can permanently damage the heart. This cardiac toxicity affects up to 20% of…
Brain cancer patients face a fundamental therapeutic challenge: most promising drugs cannot cross the blood-brain barrier, leaving tumors essentially…
CAR T cell therapy for multiple myeloma has reached a critical juncture where understanding why some patients achieve durable remissions while others relapse…
A devastating discovery about childhood brain cancer reveals how the brain's own immune system becomes corrupted to fuel tumor spread. Diffuse midline glioma…
The fundamental promise of colorectal cancer screening—that early detection saves lives—faces scrutiny from a landmark Swedish trial challenging decades of…
Precision cancer treatment may advance significantly with the development of nanoscale drug carriers that simultaneously deliver chemotherapy and provide…
The assumption that cancer treatments only target tumor cells while leaving healthy tissue largely unscathed faces a significant challenge. This finding…
Chemical contamination from everyday products may be quietly undermining metabolic health in ways that predispose women to diabetes. This finding challenges…
Four plant compounds—curcumin, resveratrol, epigallocatechin gallate (EGCG), and genistein—demonstrate the ability to disrupt cancer stem cell (CSC) signaling…
Two sophisticated imaging technologies could fundamentally transform how physicians detect, stage, and treat advanced prostate cancer, potentially improving…
Pancreatic cancer's notorious resistance to treatment may finally face a formidable challenge. The disease kills roughly 50,000 Americans annually, with most…