Found 739 results for "cancer"
National Cancer Institute surveillance data spanning 2010-2019 reveals a striking bifurcation in early-onset malignancies: while 14 cancer types increased in a…
NIH investigators identified specific tissue alterations that predict both aggressive breast cancer development in women with benign breast conditions and wors…
Clinical evidence demonstrates that subsidized fruit and vegetable programs yield quantifiable health improvements across diverse populations. Participants rec…
Researchers have determined the three-dimensional crystal structure of somatostatin receptor 3 (SSTR3), revealing precise molecular binding sites and conformat…
Analysis of 7,619 East Asian genomes identified nearly 29,000 novel methylation quantitative trait loci (mQTLs) that regulate DNA methylation patterns differen…
Researchers compiled 748,679 single cells from multiple acute myeloid leukemia studies to map how age influences gene expression patterns in t(8;21) AML, a sub…
The FDA has authorized pembrolizumab combined with paclitaxel, optionally with bevacizumab, for treating recurrent ovarian cancers expressing PD-L1 protein. Th…
Chronic stress triggers the formation of a previously unknown neutrophil subtype called cancer stress-primed (CSP) neutrophils, characterized by elevated expre…
Mendelian randomization analysis of 738,000 individuals confirms that elevated BMI causally increases kidney cancer risk by 68% per 5-unit BMI increase, with w…
The CDC has launched the National Firefighter Registry, which aims to become the largest registry of its kind in the United States. The registry invites all U.…
Researchers have pinpointed the MERTK receptor tyrosine kinase as a potential drug target for ZFTA-RELA fusion-positive ependymomas, aggressive pediatric brain…
Age-related decline in natural killer cell function stems from disrupted glycolysis and mitochondrial metabolism, according to new mechanistic research. Scient…
Laboratory experiments reveal quercetin activates the UBC6 enzyme, which orchestrates a cascade that degrades AURKA protein and activates AMPK signaling in ova…
Parasitic wasps deploy a viral-derived protein tyrosine phosphatase that specifically targets Rad9A, a critical cell cycle checkpoint protein, effectively hija…
Researchers have successfully modified CD4+ T cells with chimeric antigen receptors (CARs) to specifically recognize and target amyloid-β plaques characteristi…
MAPKAPK2, a stress-responsive kinase in the p38 signaling pathway, determines whether MEK1/2 inhibitors succeed or fail against colorectal cancer cells under m…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from preventable causes, representing the most e…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from preventable causes, representing the most e…
A computational framework successfully distinguishes between benign and pathogenic single amino acid substitutions in proteins, addressing a critical gap in ca…
Researchers have developed methods to selectively eliminate specific populations of senescent cells while preserving those that contribute to tumor suppression…