Found 739 results for "cancer"
Platinum chemotherapy triggers cellular senescence in ovarian and lung cancer cells, paradoxically promoting malignancy through TGFβ ligand secretion. González…
Metastatic cancer cells actively acquire mitochondria from surrounding immune cells through a previously uncharacterized transfer mechanism, essentially comman…
The ATR/CHK1 signaling cascade can initiate genome protection responses even when stripped of RPA protein complexes, traditionally considered essential for pat…
A novel radiopharmaceutical demonstrates efficacy against small-cell lung cancer and neuroendocrine prostate cancer, two notoriously aggressive malignancies th…
Marcel Deckert's team at INSERM in Nice has identified USP9X as a critical vulnerability in melanoma's adaptive machinery. This deubiquitinating enzyme stabili…
Marcel Deckert's team at INSERM Nice has identified USP9X as a critical vulnerability in melanoma progression, where this deubiquitinating enzyme stabilizes th…
The MET-PREVENT trial enrolled over 1,000 participants to test whether metformin could delay onset of cardiovascular disease, cancer, dementia, and other age-r…
Scientists have engineered circular RNA structures that form self-looping configurations, demonstrating enhanced stability and prolonged therapeutic activity c…
French researchers have mapped the mechanisms by which mitochondria migrate between adjacent cells, particularly within tumor environments. This intercellular…
An international expert panel has established the first formal clinical definitions and assessment frameworks for loneliness specifically in older cancer patie…
Researchers developed specialized liposomes containing triphenylphosphonium (TPP3) that successfully deliver resveratrol and Trolox antioxidants directly to mi…
The TROFFi trial represents a groundbreaking application of senolytic therapy, testing whether fisetin at 20 mg/kg daily can reverse chemotherapy-induced physi…
vCATCH technology achieves single-cell resolution mapping of covalent drug binding sites across intact mammalian tissues, offering unprecedented visualization…
University of South Florida researchers identified elevated omega-6 fatty acid concentrations within colorectal tumor tissue, demonstrating a direct inflammato…
Trastuzumab deruxtecan demonstrated superior invasive disease-free survival compared to standard trastuzumab in patients with HER2-positive early breast cancer…
Clinical trial data reveals that time-limited chronic lymphocytic leukemia treatment produces equivalent survival outcomes compared to indefinite therapy regim…
The dual-drug approach combining trastuzumab deruxtecan with pertuzumab demonstrated enhanced progression-free survival compared to standard HER2-targeted ther…
Enzalutamide, an androgen receptor inhibitor, demonstrated significant survival benefits in men with biochemically recurrent prostate cancer following initial…
A compound initially identified in cancer drug screening has demonstrated dual efficacy against Huntington's disease pathology and calcium oxalate kidney stone…