Found 81 results for "brain health"
A six-year longitudinal study of 746 older adults with metabolic syndrome identified specific gut bacterial patterns that mediate the Mediterranean diet's cogn…
Cortical astrocytes expressing lipoprotein receptor-related protein 4 (LRP4) represent a specialized GFAP-negative subpopulation that clusters along the brain'…
Cross-species research reveals that social isolation and loneliness operate through a destructive feedback cycle, where isolation impairs cognitive control and…
Understanding how blood reaches every neuron in the brain has profound implications for preventing cognitive decline and optimizing brain health throughout agi…
Researchers simulated 20,000-person cohorts across 500 replications to quantify how preclinical dementia phases bias observational studies examining BMI's rela…
Analysis of UK Biobank data revealed that highest exposure to PM2.5 fine particulate matter increases dementia risk by 14%, with nitrogen oxides (NOx) raising…
Adolescent mice subjected to three months of social isolation developed anxiety, depression, and severe social memory deficits, but intranasal oxytocin treatme…
Cyclin-dependent kinase-like 5 (CDKL5) regulates synaptic plasticity through liquid-liquid phase separation, a mechanism where proteins spontaneously organize…
Glycogen Synthase Kinase 3β emerges as a master coordinator of axonal architecture by regulating microtubule organization through interactions with Shot and Ta…
Variation in how quickly blood moves through individual brain capillaries—termed capillary transit time heterogeneity—appears to significantly influence oxygen…
Eliminating growth hormone receptors specifically in fat tissue dramatically protected aged mice from brain deterioration and cognitive decline. The interventi…
The widespread practice of daily low-dose aspirin for cardiovascular protection may not extend meaningful brain benefits to healthy older adults, challenging a…
Chinese researchers have identified lactylation—a recently discovered epigenetic modification—as a key mechanism through which neurotoxins trigger the death of…
Larval zebrafish demonstrate sophisticated energy-optimization algorithms in their neural motor circuits, selectively modulating movement patterns to maximize…
Cryo-electron microscopy reveals that Munc13-1, a critical protein orchestrating neurotransmitter release, assembles into trimeric clusters on phospholipid-ric…
Elevated circulating β-hydroxybutyrate (BHB) concentrations demonstrate significant association with reduced cognitive deterioration risk, providing compelling…
Presbycusis affects two-fifths of adults past 65, yet many dismiss auditory deterioration as inevitable aging rather than seeking intervention. The sensory def…
Analysis of nearly 125,000 UK Biobank participants reveals menopause correlates with measurable shrinkage in gray matter volumes within the medial temporal lob…
Monthly cash payments of approximately $20 preserved cognitive function and reduced dementia risk among adults aged 40-79 in rural South Africa, according to l…
National Institute on Aging researchers project that individuals reaching age 55 today face a 42% lifetime probability of developing dementia, with total cases…