Found 2029 results for "cancer"
Colorectal cancer remains one of the most preventable malignancies when precursor lesions are caught early — yet not all polyps carry the same risk profile…
Esophageal cancer remains one of the most lethal malignancies worldwide, with five-year survival rates stubbornly below 20% in most populations — a stark…
For the millions of adults who undergo colonoscopy and have adenomas removed, the question of how soon to return for surveillance is more than logistical — it…
Childhood and young-adult brain cancers rarely attract repurposed drug breakthroughs, making this Nature Medicine finding particularly compelling. Diffuse…
Two decades of hard-won progress against HIV may be quietly unraveling — and the mechanism is partly invisible in conventional epidemiology. Intimate partner…
For women with ER-positive advanced breast cancer whose tumors develop ESR1 mutations during first-line therapy, the question of whether switching treatments…
Mesothelioma ranks among oncology's most intractable diagnoses, with median survival measured in months and few second-line options after platinum-based…
Understanding how cancer cells self-organize into tissue-like structures may be one of the most underappreciated frontiers in oncology. Pancreatic ductal…
Understanding why some tumors respond to immunotherapy while others evade it remains one of oncology's most pressing unsolved problems. A new systems biology…
A protein long confined in immunology textbooks to antiviral defense turns out to play a parallel role in one of cell biology's most fundamental stress…
For decades, the androgen receptor's CAG repeat polymorphism has sat at the edge of prostate cancer research — statistically interesting but mechanistically…
Most cancer treatments target tumor growth directly, but metastasis — the spread of cancer cells through tissue — is responsible for the vast majority of…
Protein quality control is one of biology's most elegant unsolved problems: how does a cell simultaneously permit wide variation in protein synthesis speeds…
Understanding why immune cells lose their cancer-fighting capacity is one of the central puzzles in oncology. T cell exhaustion — the gradual functional…
Triple-negative breast cancer remains one of oncology's most difficult treatment puzzles — aggressive, heterogeneous, and responsive to immunotherapy in only…
Brain cancer's relationship with the neurons it inhabits has long been suspected as a driver of malignancy, but the chemical messengers enabling tumors to…
For the millions living with myasthenia gravis, current treatments are a blunt instrument — broad immunosuppression that suppresses the entire immune system…
For the roughly 83,000 Americans diagnosed with bladder cancer each year, radical cystectomy — surgical removal of the bladder — has long been the reflexive…
Ionizing radiation at 20 Gy triggers atrial fibrillation in mice through a precise molecular cascade: DNA damage activates ATM/ATR kinases, driving GATA4…
For populations facing environmental stress or demographic bottlenecks, the genetic quality of survivors may matter as much as their numbers. A foundational…