Studies
TFPI2 Protein Boosts NK Cell Attack on Glioblastoma via Dual Mechanism
Glioblastoma remains one of the most treatment-resistant cancers, with median survival under 15 months even with aggressive therapy. A newly identified…
Search Results: "cancer"
Found 2031 results for "cancer"
⚕️ Synthesized briefings — original sources linked for full context.
Longevity
Mathematical Model Maps JAK2V617F Clonal Dynamics in Asymptomatic General Population
Most adults assume cancer appears suddenly, but mounting evidence reveals that certain blood cancers incubate silently for decades through a process called…
Studies
IMPDH2 Inhibition Cuts Brain Metastasis Without Harming Immune Defenses
Brain metastases represent one of oncology's most intractable challenges — not because they are rare, but because even the best available interventions remain…
Studies
Dual Epigenetic Blockade Restores Immune Attack on Drug-Resistant Prostate Tumors
For men whose prostate cancer has become impervious to hormone therapy, treatment options narrow dramatically — and the molecular reasons why have remained…
Studies
Chromosomal Instability Drives Tumor Growth Via Neighboring Healthy Cells
Cancer treatment strategies built on destabilizing tumor chromosomes may be more complicated than previously assumed — and understanding why could reshape how…
Studies
Radiotheranostic Cancer Therapy Shows Promise But Cost-Effectiveness Evidence Remains Thin
As precision oncology increasingly captures headlines, a quieter revolution in cancer treatment is raising an urgent question that clinicians and payers alike…
Studies
CTCs Track Response to TROP2/HER2 ADCs in Metastatic Breast Cancer but Target Expression Does Not Predict Outcomes
For the millions of women with metastatic breast cancer, knowing whether a targeted therapy is actually reaching and killing tumor cells — in real time…
Longevity
45,454 Gut Microbiomes Link Medication-Associated Oral Bacteria to Aging-Disease Microbiome Overlap
A computational re-examination of 45,454 gut microbiomes across 141 studies identified 15 microbial taxa simultaneously enriched in aging and depleted in…
Studies
ENO1-HDAC1 Coupling Regulates Histone Lactylation and Oncogene Transcription in Cancer Cells
Epigenetics rarely generates headlines outside specialist circles, yet this particular discovery touches something with direct health relevance: the molecular…
Longevity
p53 Cell-Cycle Genes Gtse1 and Cdkn1a Are Critical Effectors in Mouse Model of Constitutive p53 Activation
Understanding what actually executes p53's tumor-suppressing and aging-related commands inside living organisms—not just in cell cultures—has been one of…
Studies
Drug-Binding Sites Reshape Microtubule Geometry, Altering Motor Protein Recognition
Every cell in the human body depends on microscopic protein highways called microtubules to move cargo, divide chromosomes, and generate mechanical force…
Studies
Skin Epithelial Cells Generate Neuron-Like Voltage Spikes After Injury
The assumption that rapid long-range electrical signaling is exclusive to neurons may need fundamental revision. Evidence that ordinary skin and tissue lining…
Studies
Blood Cancer Survivors Face Up to 4x Higher Heart Failure Risk Decades Later
As blood cancer survival rates climb, a critical and underappreciated threat is emerging in the decades that follow remission: cardiovascular disease. For the…
Longevity
Lifestyle Medicine Linked to Reduced Long-Term Risks for Cancer Survivors Across Five Domains
For the roughly 18 million cancer survivors in the United States alone, crossing the finish line of active treatment is not the end of the health story — it…
Studies
Dual CXCR4-PD-1 Blockade Unlocks T-Cell Attack on Rare Liver Cancer
Young adults diagnosed with fibrolamellar carcinoma face a frustrating paradox: their tumors carry a highly recognizable oncogenic signature, yet the immune…
Studies
71% of Cancer Patients Report Unmet Rehabilitation Needs Despite Clinic Access
Cancer survival rates have improved dramatically over recent decades, yet the conversation about what survival actually looks like for patients—physically…
Studies
EUS Evolves Into Precision Diagnostic Platform With AI and Liquid Biopsy
For adults navigating pancreatic disease, liver conditions, or gastrointestinal cancers, the tools physicians use to detect and characterize disease are…
Studies
Whole-Genome Sequencing Reveals Hidden Cancer Risk Variants Across 14,765 Patients
For every individual who suspects a hereditary cancer risk, there are likely many more carrying actionable germline variants who were never referred for…
Nutrition
Sucralose May Disrupt Gut-Immune Axis, Compromising Cancer Immunotherapy Response
For the millions of adults who routinely consume zero-calorie sweeteners while managing weight or blood sugar, the assumption that sucralose is biologically…
Studies
Precision Oncology Reshapes Treatment Landscape for Two Lethal GI Cancers
Two of oncology's most formidable diagnoses may be entering a new era — not through a single breakthrough, but through the convergence of molecular profiling…