PARP Inhibitor Plus Antiangiogenic Drug Extends Survival in BRCA Breast Cancer
The FABULOUS trial demonstrates that combining fuzuloparib (a PARP inhibitor) with apatinib (an angiogenesis inhibitor) significantly improves progression-free…
Found 1259 results for "cancer"
The FABULOUS trial demonstrates that combining fuzuloparib (a PARP inhibitor) with apatinib (an angiogenesis inhibitor) significantly improves progression-free…
The MetaCURE trial tested an intensive multimodal approach combining apalutamide-based hormone therapy, surgical resection, and targeted radiation in 65 men wi…
Three-dimensional laboratory models incorporating patient-derived tissues now replicate the complex cellular environment surrounding triple-negative breast can…
Analysis of 801 multiple myeloma patients revealed that 8.7% developed atrial fibrillation after autologous stem cell transplantation, with median onset occurr…
Medicare patients who underwent colon or lung cancer surgery at hospitals that eventually closed experienced significantly worse outcomes compared to those tre…
CRISPR-edited human cord blood stem cells carrying the GATA2-R398W mutation display severe mitotic dysfunction and accelerated aging signatures that compromise…
Researchers examining 2,400 cancer patients found that financial burden from treatment significantly undermines life satisfaction, with hope serving as a criti…
Bioengineers have created artificial liver environments using decellularized extracellular matrix scaffolds that successfully induce dormancy in colorectal can…
Advanced hormone receptor-positive breast cancer, representing the majority of metastatic cases, now benefits from genomic-driven treatment selection. Research…
Beyond its established role in immune suppression, PD-L1 demonstrates direct tumor-promoting functions in non-small cell lung cancer through a previously uncha…
Circulating tumor DNA levels in blood plasma accurately predicted survival outcomes in 97 men with metastatic castration-resistant prostate cancer receiving ca…
Analysis of over 1,000 patient samples and mouse models reveals that pregnancy followed by a complete lactation and weaning cycle establishes lasting CD8+ T ce…
Analysis of mammography data spanning 13 years reveals AI systems achieve comparable sensitivity to human radiologists while potentially reducing false positiv…
Scientists developed lanthanide nanoparticles that use near-infrared light to selectively reprogram M2-like tumor-associated macrophages in glioblastoma, enhan…
Analysis of 171 studies across two decades reveals 59 distinct barriers and facilitators affecting oral nutritional supplement adherence among malnourished pat…
Understanding how viruses hijack cellular machinery could unlock new therapeutic strategies for preventing persistent infections that lead to cancer. Human pap…
Researchers identified small nucleolar RNAs (snoRNAs) as potential blood biomarkers for radiation-induced senescence in glioblastoma, the most aggressive brain…
Focus groups with 31 Black and Hispanic men with localized prostate cancer and their partners identified four key barriers to adopting heart-protective diets l…
Meta-analysis of five randomized trials involving 7,246 postoperative colorectal cancer patients demonstrates that anti-inflammatory medications reduce disease…
An off-the-shelf neoantigen vaccine targeting Lynch syndrome has demonstrated both safety and immunogenicity in clinical testing, marking a significant step to…