Studies
Irradiated Tumor Fibroblasts Enter Senescence Yet Fuel Cancer Regrowth
Radiation therapy's failure to cure a third of advanced head and neck cancers has long puzzled oncologists, and this research points toward a cellular…
Search Results: "cancer"
Found 1694 results for "cancer"
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Studies
Explainable AI Skin Diagnostics Help Doctors But May Mislead Patients
The promise of AI-assisted diagnostics hinges on a critical assumption: that making AI more transparent improves outcomes for everyone who uses it. New…
Longevity
Senescent Cells Drive HFpEF via SASP Inflammation: Senolytics Offer Targeted Hope
Heart failure with preserved ejection fraction is one of cardiology's most frustrating frontiers — affecting nearly half of all heart failure patients, with…
Studies
ctDNA Tumor Fraction Predicts Who Needs Chemotherapy Added to Immunotherapy in Lung Cancer
The longstanding clinical puzzle of when to add chemotherapy to immunotherapy in advanced lung cancer may have a more precise molecular answer. For the…
Studies
AI-Imaging Model Links Liver Cancer Recurrence Risk to Pyruvate Metabolism Disruption
For the roughly 70–80% of hepatocellular carcinoma patients who experience tumor recurrence within five years of surgery, the window for intervention is…
Studies
Personalized mRNA Cancer Vaccines Show Meaningful Recurrence Reduction Across Tumor Types
For decades, the idea of teaching the immune system to recognize and destroy a patient's own tumor has been more promise than reality — but the therapeutic…
Studies
AI Framework Cuts Lung Cancer Recurrence Labeling Error by Half
The quality of cancer outcomes research depends almost entirely on the accuracy and completeness of clinical registries — and those registries are riddled…
PREPRINTStudies
BRCA1/2 Breast Cancer Survivors Show Lower CVD Rates—But Competing Risks Explain Why
Among 32 matched cohort pairs of breast cancer survivors in the Stockholm-Gotland region (2008–2019), women carrying germline BRCA1/2 mutations experienced…
Studies
Study Maps Protective Niches Harboring Dormant Breast Cancer Cells Near Immune and Stromal Cells
Understanding why breast cancer returns years after apparent remission is one of oncology's most vexing problems. This research reframes that question…
Studies
MYC Phosphorylation at Serine 62 Drives DNA Repair in Cancer Cells
One of oncology's most persistent puzzles is how MYC — the transcription factor gone rogue in virtually every human tumor — can simultaneously damage DNA and…
Supplements
0.1 μM Resveratrol Fully Reverses Radiation-Induced Endothelial DNA Damage In Vitro
At a strikingly low concentration of 0.1 μM — far below typical supplementation doses — resveratrol completely rescued ionizing radiation (IR)-induced DNA…
Nutrition
Mediterranean Diet Linked to Lower Risk Across 7 Cancer Types in Large Meta-Analysis
Across 126 studies enrolling more than 8 million participants, greater adherence to the Mediterranean diet was associated with statistically significant…
Studies
LARS Enzyme Drives Liver Cancer Growth by Suppressing Cellular Senescence
Understanding why some liver cancers grow aggressively while resisting natural cell-death signals has been a persistent challenge in oncology. The discovery…
Longevity
Lung Aging Mechanisms Linked to COPD, Fibrosis, and Cancer Resistance
Chronic lung disease is not simply wear and tear — it is aging biology gone awry in specific, targetable ways. As pulmonary medicine reaches a point where…
Studies
Random Forest Model Predicts Liver Cancer Risk from Routine Clinical Data
Liver cancer remains one of the most lethal malignancies precisely because it is so rarely caught early. If a standard clinical visit — the kind millions of…
Longevity
Combined Training + Probiotics Slash Fusobacterium, Restore mTOR Signaling in Aged Rats
In aged male Wistar rats, eight weeks of moderate-intensity resistance training combined with a multi-nutrient stack (Lactobacillus plantarum, Bifidobacterium…
Studies
Fatty Acid Enzyme ACSS2 Shields EGFR From Degradation, Fueling Liver Cancer Drug Resistance
Acquired resistance to first-line therapies remains one of the most stubborn barriers in advanced liver cancer treatment. Understanding exactly how tumor…
Studies
Next-Generation Intratumoral Agents Show Durable Responses in Checkpoint-Resistant Melanoma
For patients with advanced melanoma who have exhausted standard immune checkpoint inhibitor options, the prospect of meaningful, durable remissions has…
Studies
PRISM2 AI Matches Clinical Cancer Detection Across Pathology Without Task-Specific Training
The prospect of a single AI system capable of reading pathology slides and answering clinical questions at physician-grade accuracy — without being retrained…
Wellbeing
Half of Childhood Leukemia Survivors Report Depression or Anxiety in Adulthood
Surviving childhood cancer is rightly celebrated — but the long shadow it casts on adult neurocognitive and psychological health is only beginning to be…