Cellular Atlas Reveals Mechanisms Linked to Cilta-cel vs Ide-cel Outcomes in Myeloma
CAR T cell therapy for multiple myeloma has reached a critical juncture where understanding why some patients achieve durable remissions while others relapse c…
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CAR T cell therapy for multiple myeloma has reached a critical juncture where understanding why some patients achieve durable remissions while others relapse c…
The global healthcare system faces an unprecedented challenge as cancer cases surge worldwide while the workforce needed to diagnose and treat them fails to ke…
Chemical contamination from everyday products may be quietly undermining metabolic health in ways that predispose women to diabetes. This finding challenges th…
Two sophisticated imaging technologies could fundamentally transform how physicians detect, stage, and treat advanced prostate cancer, potentially improving su…
Pancreatic cancer's notorious resistance to treatment may finally face a meaningful challenge. With five-year survival rates below 12%, this malignancy represe…
Pancreatic cancer's notorious resistance to treatment may finally face a formidable challenge. The disease kills roughly 50,000 Americans annually, with most p…
The intersection of genetic risk factors may fundamentally alter how clinicians assess breast cancer susceptibility in men, particularly those developing the d…
Pancreatic ductal adenocarcinoma remains one of medicine's most formidable challenges, with five-year survival rates below 10% and limited therapeutic options…
Chronic stress wreaks havoc on multiple body systems simultaneously, but medicine has lacked precise tools to measure this cumulative damage before diseases ma…
The precision of immune surveillance against cancer depends on molecular interactions far subtler than previously understood. When T cells patrol for threats,…
Understanding how to disable c-Myc could revolutionize cancer treatment, given this oncoprotein drives tumor growth in roughly seven out of ten cancers. The ch…
The persistence of aggressive breast cancer patterns in Black women demands urgent attention from both clinicians and patients navigating early detection strat…
Targeted cancer therapy takes another step forward with evidence that patients harboring specific genetic alterations in their tumors may benefit from precisio…
Resveratrol-loaded liposomes significantly protected ovarian function in mice exposed to cyclophosphamide chemotherapy by activating the HIGD1A/NF-κB/SOD2 sign…
Four plant compounds—curcumin, resveratrol, epigallocatechin gallate (EGCG), and genistein—demonstrate the ability to disrupt cancer stem cell (CSC) signaling…
Glioblastoma represents medicine's most formidable oncological challenge, with median survival rarely exceeding 15 months despite aggressive treatment. The can…
Extracellular vesicles from embryonic stem cells successfully reversed chemotherapy-induced ovarian failure in mice, restoring estrous cycles, fertility, and f…
Triple-negative breast cancer represents one of the most aggressive malignancies, with limited treatment options and high metastatic potential that devastates…
Analysis of 4 million breast cancer survivors reveals that GLP-1 receptor agonists emerge as a promising intervention beyond traditional lifestyle modification…
PTEN protein loss in prostate cancer triggers extensive stromal remodeling through enhanced transforming growth factor beta (TGF-β) signaling and senescent cel…