Found 2029 results for "cancer"
Predicting which cancer patients will actually respond to immunotherapy remains one of oncology's most pressing unsolved problems — billions are spent on…
Small-cell lung cancer's brutal biology — rapid progression, early metastasis, and near-universal resistance to second-line chemotherapy — has made it one of…
Immune checkpoint inhibitors transformed lung cancer treatment, yet most patients who initially respond eventually relapse — and understanding exactly why has…
The prospect of testing thousands of drug combinations in a living tumor cell — without touching a single patient — has long been a computational biology…
Pancreatic cancer remains one of oncology's most intractable challenges, with five-year survival rates stubbornly below 12% and near-universal resistance to…
Pretreatment with ambrisentan, a selective endothelin A receptor antagonist approved for pulmonary arterial hypertension, significantly protected H9c2…
For decades, small cell lung cancer was considered a monolithic, uniformly lethal disease — one that simply didn't yield to the targeted therapy revolution…
A systematic review of 46 structurally diverse terpenoids — spanning monoterpenoids, diterpenoids, triterpenoids, and sesquiterpenoids — reveals that most…
A persistent and widening gap in adolescent HPV vaccination coverage carries direct implications for future cervical, oropharyngeal, and other HPV-associated…
The longstanding frustration with CAR-T cell therapy in solid tumors — poor penetration, antigen escape, hostile microenvironments — has pushed researchers…
For the roughly one-third of adults worldwide living with at least one chronic condition, the gap between what happens inside a clinic and what happens in…
Senescent cells exploit the immune checkpoint protein PD-L2 to evade immune clearance, accumulating with age and driving metabolic and physical decline. In…
Most cancer-prevention messaging around beverages focuses on alcohol or sugar content — but the temperature at which people drink their tea or coffee may be…
For women with triple-negative breast cancer — one of the most aggressive and hardest-to-treat subtypes — knowing whether chemotherapy is working after just…
Breast cancer risk prediction has long relied on static snapshots — a single mammogram read at a single point in time. A model that instead watches how subtle…
For men with metastatic castration-resistant prostate cancer, PARP inhibitors represented a hard-won therapeutic advance — but only for a subset of patients…
Radiation therapy is one of oncology's most foundational tools, yet a paradox has quietly undermined its effectiveness: the very cellular damage it inflicts…
Senescent CD8+ T cells accumulate in ulcerative colitis (UC) mucosa through a discrete metabolic cascade: NAD+ depletion triggers mitochondrial dysfunction…
Cancer clinical trials are notorious for their staggering operational burdens—dense protocols, exhaustive data fields, and narrow eligibility windows that…
Understanding how cells suppress autophagy — the cellular recycling program intimately tied to aging, cancer, and neurodegeneration — has taken on new urgency…