Found 1694 results for "cancer"
The boundary between immune tolerance and immune attack is finely calibrated by a small population of regulatory T cells (Tregs), and disrupting that balance…
For the estimated 1-2% of the global population living with vitiligo, narrowband UVB phototherapy offers meaningful hope for repigmentation — yet the same…
One of the most stubborn obstacles in brain cancer treatment is not the tumor itself — it is the blood-brain barrier, a molecular fortress that blocks roughly…
Precision cancer immunotherapy has long been constrained by a fundamental computational bottleneck: identifying which mutated protein…
Hereditary breast cancer risk is not a single genetic story — the mutations that matter depend heavily on the tumor's molecular subtype, and conflating…
Intracellular complement proteins C3 (intC3) and C5 (intC5) — components of what is now termed the 'complosome' — engage in extensive crosstalk with mTOR…
The intersection of lifestyle interventions and cancer treatment efficacy is one of the most consequential frontiers in oncology. If metabolic states shaped…
Understanding how cancer cells hijack the body's growth machinery is one of the central puzzles of oncology — and the answer increasingly points to molecular…
Amyotrophic lateral sclerosis remains one of the most devastating and least tractable neurodegenerative diseases, with median survival measured in years from…
Hormone manipulation has long been the cornerstone of advanced prostate cancer management, but the cardiovascular toll of conventional androgen deprivation…
For the hundreds of thousands of women diagnosed annually with epithelial ovarian cancer, PARP inhibitors represent a frontline defense — yet most patients…
The window of greatest vulnerability to chemical carcinogens may begin before birth — a finding that fundamentally reshapes how researchers think about breast…
One of oncology's most troubling paradoxes is that the treatments designed to kill cancer may simultaneously create conditions that help it spread. This…
For anyone tracking cancer immunotherapy, the slow crawl of oncolytic virotherapy toward a second FDA approval reveals a striking gap between biological…
For decades, chronic low-grade inflammation in older adults was treated as a background condition — an inevitable consequence of aging with modest clinical…
Locally advanced prostate cancer poses a stubborn clinical challenge: tumors that spread diffusely within and beyond the prostate gland are notoriously…
Across 674 serum samples from the Singapore Longitudinal Ageing Studies (n=6,050), proteomics profiling of over 2,400 proteins identified 52…
Precise control over how cells destroy their own proteins sits at the heart of aging, neurodegeneration, and cancer biology. When the proteasome — the cell's…
Cellular membranes are far more than passive barriers — they serve as dynamic signaling platforms whose lipid composition is tightly regulated. A specific…
For decades, the textbook model of G-protein-coupled receptor (GPCR) signaling placed all meaningful activity at the plasma membrane — a tidy picture that…