Found 1694 results for "cancer"
Pancreatic cancer cells exploit the UBE3A protein to resist cellular senescence by degrading mH2A1 histone variants at the K167 residue, which normally…
Metabolic dysfunction-associated steatotic liver disease affects nearly one billion people globally, yet therapeutic options remain limited despite the…
The path from pancreatic injury to cancer may be more predictable than previously understood, potentially opening new windows for early intervention in one of…
Female mice generated significantly stronger antibody responses to influenza vaccination than males through estradiol-driven metabolic reprogramming of B…
Three-dimensional laboratory models incorporating patient-derived tissues now replicate the complex cellular environment surrounding triple-negative breast…
The MetaCURE trial tested an intensive multimodal approach combining apalutamide-based hormone therapy, surgical resection, and targeted radiation in 65 men…
The FABULOUS trial demonstrates that combining fuzuloparib (a PARP inhibitor) with apatinib (an angiogenesis inhibitor) significantly improves…
Analysis of 801 multiple myeloma patients revealed that 8.7% developed atrial fibrillation after autologous stem cell transplantation, with median onset…
Bioengineers have created artificial liver environments using decellularized extracellular matrix scaffolds that successfully induce dormancy in colorectal…
Researchers examining 2,400 cancer patients found that financial burden from treatment significantly undermines life satisfaction, with hope serving as a…
CRISPR-edited human cord blood stem cells carrying the GATA2-R398W mutation display severe mitotic dysfunction and accelerated aging signatures that…
Medicare patients who underwent colon or lung cancer surgery at hospitals that eventually closed experienced significantly worse outcomes compared to those…
Analysis of over 1,000 patient samples and mouse models reveals that pregnancy followed by a complete lactation and weaning cycle establishes lasting CD8+ T…
Circulating tumor DNA levels in blood plasma accurately predicted survival outcomes in 97 men with metastatic castration-resistant prostate cancer receiving…
Beyond its established role in immune suppression, PD-L1 demonstrates direct tumor-promoting functions in non-small cell lung cancer through a previously…
Advanced hormone receptor-positive breast cancer, representing the majority of metastatic cases, now benefits from genomic-driven treatment selection…
Analysis of mammography data spanning 13 years reveals AI systems achieve comparable sensitivity to human radiologists while potentially reducing false…
Cancer stem cells that initiate breast tumors appear to originate from different mammary cell populations depending on patient age, with older women's tumors…
HDAC3, a histone deacetylase enzyme, directly regulates the Hippo signaling pathway through acetylation modifications of the Hpo protein, revealing a novel…
A novel imaging technique combines TROP2 protein targeting with near-infrared fluorescence to provide real-time visualization of cancer boundaries and lymph…